组织工程与重建外科杂志 ›› 2015, Vol. 11 ›› Issue (1): 23-25.doi: 10.3969/j.issn.1673-0364.2015.01.006

• 论著 • 上一篇    下一篇

皮肤纤维化测量仪对淋巴水肿疾病的诊断价值

韩凌华,刘宁飞,于子优,汪立,陈佳佳   

  1. 上海交通大学医学院附属第九人民医院整复外科淋巴水肿中心
  • 发布日期:2020-07-23

The Value of Skin Fibro Meter in the Diagnosis of Lymphedema Disease

HAN linghua,LIU Ningfei,YU Ziyou,WANG Li,CHEN Jiajia   

  1. Center of Lymphedema; Department of plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine;
  • Published:2020-07-23
  • Contact: 国家自然科学基金项目(81272146);上海市科委科技攻关计划项目(12401900504)

摘要: 目的探索皮肤纤维化测量仪(Skin Fibro Meter,SFM)对淋巴水肿疾病的诊断价值。方法将16例淋巴水肿患者和20例健康成人,分别设为淋巴水肿组和正常对照组。采用SFM对淋巴水肿组患者分别进行健、患肢测试,另外还对淋巴水肿组患者进行健、患肢分段组织水肿(水分)测量,并与正常对照组进行比较。结果淋巴水肿组患者健侧纤维化平均值为(0.07±0.01),患侧纤维化平均值为(0.13±0.05),两者差异显著(P<0.000 1);淋巴水肿组患者患肢水分平均值为(6.4±3.76),健侧平均值为(4.47±2.09),健、患侧水分平均值差异显著(P=0.002),水分比率值为43.2%,水分比率和纤维化差值呈现正相关趋势。正常对照组纤维化平均值为(0.06±0.02),与淋巴水肿组患肢比较,差异显著(P<0.000 1);结论 SFM为淋巴水肿的诊断提供了可靠的依据,其诊断价值值得进一步研究和探索。

关键词: 淋巴水肿, 皮肤纤维化测试仪, 组织纤维化, 诊断价值

Abstract: Objective To explore the diagnostic value of Skin Fibro Meter (SFM) in lymphedema diseases. Methods Sixteen cases of lymphedema patients and twenty cases of healthy people were included in this study as lymphedema group and control group respectively. With Skin Fibro Meter (Delfin company, Finland), SFM test was performed on bilateral limbs of lymphedema group and control group. In addition, bilateral tissue moisture content of each segment of patients in lym-phedema group was also measured. Results In lymphedema group, the average fibrosis value of healthy side was (0.07±0.01) and (0.13±0.05) of affected side (P<0.000 1). In lymphedema group, the average tissue moisture content was (4.47±2.09) in healthy side, and (6.4±3.76) in affected side (P=0.002). The moisture ratio was 43.2%and it presented a tendency of positive correlation with the D-value of fibrosis between the healthy side and affected side. The average fibrosis value was (0.06±0.02) in control group, and (0.13±0.05) in lymphedema group (P<0.000 1). Conclusion Skin Fibro Meter provides reliable basis for the diagnosis of lymphedema disease, its diagnostic value is worth further research and exploration.

Key words: Lymphedema, Skin Fibro Meter, Tissue fibrosis, Diagnosis value

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