关键词: 分裂痣, 　眼睑, 　治疗, 　激光, 　手术, 　全厚皮片, 　皮瓣 

Abstract: Divided nevus, also known as "kissing nevus", "split ocular nevus" or "panda nevus", is a rare congenital dermatological abnormality that occurs at opposite margins of the upper and lower eyelids. There is paucity of literature on this rare congenital skin abnormality, and most knowledge of the disease process comes from isolated case reports and few series reports. The purpose of this review is to summarize the timing and basic treatment of divided nevus of eyelid. Most mitotic nevi reported in the literature are of medium-size intradermal melanocyte type. Majority of divided nevi included in this review were medium sized and of the melanocytic intradermal type. Malignant transformation occurred in 6 of all the cases read. A number of reconstruction approaches have been described in the literature, including one-stage reconstruction and multi-stage sequential reconstruction. In this review, a basic approach to reconstructing these complex defects was proposed, although ultimately individuation treatment depends on the surgeon's own choice.

Key words:  , Divided nevi, 　Eyelid, 　Treatment, 　Laser, 　Surgery, 　Full-thickness grafts, 　Flap