组织工程与重建外科杂志 ›› 2023, Vol. 19 ›› Issue (1): 49-.

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外用大麦蛋白和烟酰胺复方制剂促进面部年轻化的疗效

  

  • 出版日期:2023-02-01 发布日期:2023-03-08

Effect of compound preparation of barley protein and nicotinamide on facial rejuvenation

  • Online:2023-02-01 Published:2023-03-08

摘要:

目的 评估大麦蛋白和烟酰胺复方外用护肤品改善眼周皱纹和提亮面部肤色的疗效。

方法 选取 2020 年 6月到 9 月期间就诊的有面部年轻化和提亮肤色要求的 31 名患者,应用大麦蛋白和烟酰胺复方制剂(早上 2 滴,晚上 4 滴)。4 周、8 周后随访,评估受试者眼周皱纹、皮肤弹性和黑色素指数的变化。结果 8 周后,双眼周皱纹改善显著者 21 例,有效率为 68.0%。面部图像分析结果显示,应用本产品 4 周、8 周后患者面部皱纹特征计数明显下降(P<0.05)。4 周后,患者皮肤弹性 R2 值较应用前显著升高(P<0.05)。本组患者未观察到治疗相关不良反应。

结论 外用大麦蛋白和烟酰胺复方制剂可改善皱纹和提亮肤色

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Abstract:

 Objective To evaluate the efficacy of a topical compound of barley protein and nicotinamide in anti-wrinkle
and facial brightening. Methods From June to September 2020, 31 patients with a requirement for facial rejuvenation and skin
lightening were included in the study. The topical compound of barley protein and nicotinamide was applied twice a day (2 drops
in the morning and 4 drops in the evening). The changes in periocular wrinkles, skin elasticity and melanin index were evaluated
at 4-week and 8-week follow-up. Results After 8 weeks of treatment, 21 subjects showed significant improvement in the
wrinkles around eyes, with an effective rate of 68%. VISIA showed that the number of facial wrinkles decreased significantly
after 4 and 8 weeks of application (P<0.05). The R2 value of skin elasticity was significantly higher after 4 weeks of application
(P<0.05). No treatment related side effects were observed. Conclusion Topical application of barley protein and nicotinamide
can lighten wrinkles and brighten skin.

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