组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2023, Vol. 19 ›› Issue (4): 376-379.

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健脾祛湿方治疗痰湿湿热体质患者瘢痕疙瘩的疗效观察

  

  • 出版日期:2023-08-01 发布日期:2023-09-06

Clinical observation of the effect of JianpiQushi Fang on the treatment of keloid in patients with phlegm-damp/damp-heat TCM constitution

  • Online:2023-08-01 Published:2023-09-06

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摘要： 目的　观察健脾祛湿方口服煎剂治疗痰湿 / 湿热体质瘢痕疙瘩患者的临床疗效，为瘢痕疙瘩的整体中医治 疗方案提供初步的临床证据。方法　25 例经过中医体质判定为痰湿 / 湿热体质的瘢痕疙瘩患者，予健脾祛湿方水煎 服，每日 1 剂，2 次分服，4 周一个疗程。对比观察治疗前后体质评分，瘢痕局部疼痛、瘙痒症状的变化，以及温 哥华评分变化。结果　与治疗前相比，治疗后患者的体质评分、瘢痕局部疼痛和瘙痒症状评分均有显著改善（P<0.05）， 而瘢痕温哥华评分没有显著变化（P>0.05）。结论　健脾祛湿方能有效减轻痰湿 / 湿热体质的瘢痕疙瘩患者的症状， 但对改善瘢痕外观和质地作用有限，需要与外科局部治疗相结合。

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Abstract: Objective　To explore the clinical effect of Traditional Chinese Medicine (TCM) formula “JianpiQushi Fang” in the treatment of keloid in patients with phlegm-damp/damp-heat TCM constitution, and to provide preliminary clinical evidence for TCM systemic treatment of keloid. Methods　Twenty-five keloid cases were diagnosed as phlegm-dampness/damp heat constitution by TCM constitution criteria. The patients were treated with“JianpiQushi” decoction with 1 dose daily (half dose twice a day) and continued for 4 weeks as a course of treatment. Physique score, local scar pain/pruritus symptoms, and Vancouver scar scale (VSS) score were compared before and after the treatment. Results　Compared with before treatment, the physique score, scar local pain score and pruritus symptom score were significantly improved after treatment (P<0.05), while the scar VSS score had no significant change (P>0.05). Conclusion　“JianpiQushi Fang” can effectively reduce the symptoms of keloid in patients with phlegm-damp/damp-heat TCM constitution, but its effect on improving the appearance and texture of scar is limited, suggesting that it should be combined with local surgical treatment.

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