组织工程与重建外科杂志 ›› 2025, Vol. 21 ›› Issue (6): 529-.

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内窥镜辅助下双平面假体隆乳术后NSAIDs药物相关疼痛管理的回顾性研究

  

  • 出版日期:2025-12-25 发布日期:2025-12-30

A retrospective study on NSAIDs-related pain management following endoscopically-assisted dual-plane breast implant augmentation

  • Online:2025-12-25 Published:2025-12-30

摘要:

目的 评价酮咯酸氨丁三醇注射液与注射用帕瑞昔布钠对经腋窝入路假体隆乳手术后的镇痛效果。方法
回顾性分析 2021年 12月至 2024年 9月,因小乳症行腋窝入路假体隆乳手术者 91例,根据术后所使用的非甾体类抗炎
药物(Nonsteroidal anti-inflammatory drugs,NSAIDs),随机分为酮咯酸氨丁三醇注射液组(n=57)与注射用帕瑞昔布钠组
(n=34)。对比术后第1、2天的疼痛视觉模拟评分法( Visual analogue scale,VAS)评分,并统计术后恶心呕吐等不良反应
发生率。结果 术后第 1 天,酮咯酸氨丁三醇注射液组的平均 VAS 评分显著高于注射用帕瑞昔布钠组(4.44±2.60 vs.6.40±2.17,P<0.05)。第 2 天两组 VAS 评分无明显差异(4.44±2.60 vs. 3.60±2.43,P>0.05)。术后第 1 天恶心发生率为
7.7%(7/91),呕吐发生率为 3.3%(3/91),无其他不良反应;术后第 2 天恶心发生率为 2.2%(2/91),无其他不良反应。
结论 与帕瑞西布钠相比,酮咯酸氨丁三醇在腋窝入路双平面假体隆乳术后早期具有较好的镇痛效果。

关键词:

Abstract:

Objective To evaluate the efficacy of Ketorolac Tromethamine injection versus Parecoxib sodium injection in
postoperative analgesia following transaxillary approach dual-plane prosthetic breast augmentation surgery. Methods A retrospective analysis was conducted on 91 patients with micromastia who underwent transaxillary approach dualplane implant breast augmentation surgery between December 2021 and September 2024. Patients were divided into two groups based on postoperative NSAIDs selection: the Ketorolac Tromethamine group (n=57) and the Parecoxib Sodium group (n= 34). Postoperative pain VAS scores on days 1 and 2 were compared, and the incidence of adverse reactions such as nausea and vomiting was recorded. Results On postoperative day 1, the mean VAS score in the Ketorolac Tromethamine group was significantly higher than that in the Parecoxib Sodium group (6.40±2.17 vs. 4.44±2.60,P<0.05). On postoperative day 2, no significant difference was observed between the groups (3.60±2.43 vs. 4.44±2.60,P>0.05). The incidence of nausea on the first day post-operation was 7.7% (7/91), the incidence of vomiting was 3.3% (3/91), and there were no other adverse reactions. The incidence of nausea on the second day post-operation was 2.2% (2/91), and there were no other adverse reactions. Conclusion Compared with Parecoxib Sodium, Ketorolac Tromethamine demonstrates superior analgesic efficacy in the early postoperative period for patients undergoing transaxillary approach dual-plane prosthetic breast augmentation.

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