组织工程与重建外科杂志 ›› 2025, Vol. 21 ›› Issue (6): 599-.

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硅酮凝胶联合光电技术在增生性瘢痕防治中的应用进展

  

  • 出版日期:2025-12-25 发布日期:2025-12-30

Application progress of silicone gel combined with photoelectric technology in the prevention and treatment of hypertrophic scars

  • Online:2025-12-25 Published:2025-12-30

摘要:

病理性瘢痕是皮肤受到一定深度创伤后异常纤维化修复的结局。其中,增生性瘢痕的发病率较高,常见于烧
伤、手术后,常有局部的瘙痒、疼痛及功能障碍,严重影响患者生存质量。硅酮凝胶具有良好的安全性、有效性和便捷
性,已成为各类增生性瘢痕、瘢痕疙瘩患者的治疗优选。近年来的多项研究发现,硅酮凝胶联合光电技术可协同增强疗
效。本文通过梳理循证医学证据,解析硅酮凝胶以及硅酮凝胶联合光电技术在医学美容、烧伤、外科手术、剖宫产以及
儿童瘢痕患者中的疗效与安全性,并探讨临床实践要点与注意事项,以期为瘢痕精准化综合管理提供参考。

关键词:

Abstract:

Pathological scars represent an aberrant fibrotic repair outcome following deep dermal injuries. Among them,
the incidence of hypertrophic scars is relatively high, commonly seen after burns, surgical operations and cesarean sections. These scars significantly impair patients' quality of life due to associated pruritus, pain, and functional impairment. Silicone gel has emerged as a preferred therapeutic option for hypertrophic scars and keloids, owing to its well-established safety, efficacy, and ease of use. Recent studies have demonstrated that combining silicone gel with photoelectric technologies synergistically enhances therapeutic outcomes. This review consolidates evidence-based data to evaluate the efficacy and safety of silicone gel monotherapy and its combination with photoelectric therapies across diverse clinical populations, including medical aesthetics, burn rehabilitation, surgical procedures, cesarean section scars, and pediatric scar management. Furthermore, it discusses key clinical considerations and practical recommendations to advance personalized scar management strategies.

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