组织工程与重建外科杂志

组织工程与重建外科杂志 >

2019 , Vol. 15 >Issue 6: 425 - 427

DOI: https://doi.org/10.3969/j.issn.1673-0364.2019.06.013

综述

干细胞冷冻保护剂的研究进展

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  • 上海师范大学生命科学学院；上海交通大学医学院附属第九人民医院整复外科
李青峰(E-mail:dr.liqingfeng@yahoo.com)。

收稿日期: 2019-08-16

  修回日期: 2019-09-30

  网络出版日期: 2019-12-20

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Advances of Cryoprotective Agents for Stem Cells

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  • College of Life Sciences, Shanghai Normal University; Department of Plastic and Reconstructive Surgery,Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine

Received date: 2019-08-16

  Revised date: 2019-09-30

  Online published: 2019-12-20

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摘要

干细胞具有促进组织修复与再生的作用,蕴藏着广泛的临床应用前景。低温冻存是实现干细胞长期保存的常用方法。在低温保存过程中,有效的冷冻保护剂(CPA)对于防止细胞低温损伤和保持细胞活力至关重要。本文将对干细胞冷冻保护剂的研究进展进行综述。

关键词： 干细胞; 冷冻保护剂; 冷冻损伤; 细胞活性

本文引用格式

张天钰，周双白，李青峰 . 干细胞冷冻保护剂的研究进展[J]. 组织工程与重建外科杂志, 2019 , 15(6) : 425 -427 . DOI: 10.3969/j.issn.1673-0364.2019.06.013

Abstract

Stem cell can promote tissue repair and regeneration, and has a promising potential application in clinic.Cryopreservation is a common way to achieve long-term preservation of stem cells. An effective cryoprotective agents(CPA)is vital to prevent cells from cryodamage and keep cell viability during cryopreservation process. In this paper, the recent advances in CPA for stem cells were reviewed.

Key words： Stem cells; Cryoprotective agents; Cryodamage; Cell viability

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