目的观察聚桂醇泡沫硬化剂治疗浅表静脉畸形的疗效与安全性。方法 2013年1月至2014年4月,对17例浅表静脉畸形患者采用硬化治疗。采用Tessari法制作聚桂醇泡沫硬化剂(液气比为1∶4),其中聚桂醇注射液浓度为1%。治疗4周1次,末次治疗结束后1个月,根据病灶颜色和大小进行疗效评价,同时记录治疗过程中及治疗后的不良反应。结果 17例患者平均治疗3.06次,治疗后5例病灶接近正常,7例明显好转,3例部分改善,2例轻度改善,无效0例;不良反应包括局部肿胀、疼痛、皮肤色素沉着。结论应用聚桂醇泡沫硬化剂治疗浅表静脉畸形,疗效肯定,无严重并发症,安全性高。

Objective To investigate the efficacy and safety of sclerotherapy with polidocanol foam in the treatment of superficial venous malformation (VM). Methods From January 2013 to April 2014, 17 superficial VM patients were treated by sclerotherapy. The polidocanol foam was produced by Tessari ’s method (liquid∶air=1∶4). The concentration of polidocanol used was 1%. Sclerotherapy was repeated at an interval of 4 weeks. Therapeutic outcomes were evaluated by color and size of lesions. Side-effects were both recorded during treatment and after treatment. Results The average number of sessions was 3.06. The results were excellent in 5 cases, good in 7 cases, fair in 3 cases and poor in 2 cases. Side effects including swelling, pain and transient hyperpigmentation were observed. Conclusion Sclerotherapy with polidocanol foam for superficial venous malformation is effective and safe without severe side effects.