综述

骨形态发生蛋白2/7异源二聚体的研究进展

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  • 潍坊医学院整形外科医院

网络出版日期: 2020-07-23

Research Progress of Bone Morphogenetic Protein 2/7 Heterodimer

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  • Plastic Surgery Hospital, Weifang Medical University;

Online published: 2020-07-23

摘要

骨形态发生蛋白2/7(BMP2/7)异源二聚体,较其同源二聚体具有更强的诱导成骨潜能,是目前组织工程骨研究的重要分支之一。本文介绍了异源二聚体BMP2/7诱导成骨的相关实验,比较其与同源二聚体生物活性的差异,并对相关机制进行综述。

本文引用格式

高涛,周陆陆,苗春雷,唐胜建,刘方军 . 骨形态发生蛋白2/7异源二聚体的研究进展[J]. 组织工程与重建外科杂志, 2014 , 10(6) : 355 -362 . DOI: 10.3969/j.issn.1673-0364.2014.06.015

Abstract

BMP2/7 heterodimer, a bone structure formation protein, has stronger osteogenesis inductive potential than its homodimer. So the study of BMP2/7 heterodimer has been one of the most important research directions in tissue engineering osteogenesis now. In this article, the osteo-inductive related experiments of BMP2/7 heterodimer were described, the differences of biological activity between heterodimer and homodimer were compared, and the mechanisms were overviewed.
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