Journal of Tissue Engineering and Reconstructive Surgery ›› 2023, Vol. 19 ›› Issue (6): 553-.

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Research on reasonableness of allogeneic blood transfusion in patients with autologous blood transfusion and preventive nursing efficacy of massive transfusion in orthopedic surgery for craniofacial deformity

  

  • Published:2023-12-28

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Abstract:

Objective　To understand the allogeneic red blood cell infusion in patients with autologous blood transfusion
and evaluate the reasonableness of allogeneic blood transfusion in orthopedic surgery for craniofacial deformity; To explore the
risk factors for unreasonable blood transfusion; To establish a decision-making model for reasonable allogeneic red blood cell
infusion in this type of surgery; And to assess the preventive nursing efficacy of massive transfusion. Methods　The patients who
received extensive operations on craniofacial deformity and autologous blood transfusion were selected as research objects. The
theoretical hemoglobin value after the completion of intraoperative salvaged autologous blood transfusion at the end of operations
was estimated, and unreasonable blood transfusion was defined as being greater than 100 g/L and receiving allogeneic red blood
cell infusion. The differences in various clinical indexes between unreasonable blood transfusion patients and other patients
were compared, and the risk factors related to unreasonable blood transfusion were analyzed via the regression model. Artificial
intelligence neural network algorithm was used to establish a decision-making model for reasonable allogeneic red blood cell
infusion in this type of surgery. The preventive nursing efficacy of massive transfusion was assessed by reviewing adverse
reactions in perioperative blood transfusion. Results　A total of 63 patients with intraoperative autologous blood transfusion 
were included in this study, of which the allogeneic red blood cell infusion rate was 96.83% (61/63) and the unreasonable
allogeneic red blood cell infusion rate was 36.07% (22/61). The regression model did not find relatively independent risk
factors that lead to unreasonable allogeneic blood transfusion. The area under the ROC curve in the decision-making model
for reasonable allogeneic red blood cell infusion was close to 100%. After using a lot of preventive nursing measures for blood
transfusion in this type of surgery, no serious complications related to blood transfusion occurred. Conclusion　There are many
unreasonable allogeneic red blood cell infusion phenomena in patients with autologous blood transfusion in orthopedic surgery
for craniofacial deformity. It’s suggested that the model in this study should be used to evaluate the necessity of allogeneic red
blood cell infusion at any time according to the changes of blood loss and autologous blood transfusion volume, so as to avoid
unreasonable allogeneic blood transfusion. The efficacy of preventive nursing measures for massive transfusion is definite in this
type of surgery

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