Abstract:

Objective To explore the related factors of capsular contracture of prosthetic breast augmentation. Methods

A retrospective controlled study was used to analyze the clinical data of 227 patients who underwent breast augmentation with

silicone gel prosthesis from April 2019 to January 2020. According to whether capsule contracture occurred， the patients were

divided into capsule contracture group and control group， followed up for 24 months. The age， BMI， smoking history，

lactation history， surgical approach， prosthesis brand and surface properties， whether prosthesis was too large， whether

endoscope was used， drainage volume and hematoma between the two groups were compared， and regression analysis was

performed for the factors with significant correlation. Results There were no significant differences in age， BMI， lactation

history， surgical approach， brand of prosthesis， surface traits of prosthesis， whether to use endoscope or not and drainage

volume between the two groups （P>0.05）

. Smoking history， oversized prosthesis and hematoma were significantly correlated

with the occurrence of capsular contracture （P<0.05）

. Logistic regression analysis showed that after correcting the surgical

approach， prosthesis surface properties and whether or not to use endoscopy， smoking history （OR=2.968，

95%CI：

1.385-

6.365）， oversized prosthesis （OR=6.028，

95%CI：

2.448-14.845） and hematoma （OR=14.560，

95%CI：

1.783-118.922）

were still positively correlated with capsular contracture. Conclusion Smoking history， excessive prosthesis selection and

hematoma increase the incidence of capsular contracture， and the specific mechanism needs further study.

Key words:

Breast augmentation, Smoking history, Capsular contracture, Oversized prosthesis, Hematoma