Abstract: 　 At present， the influence of material physical factors on cell fate is one of the research hotspots. Relevant studies have shown that the microscopic morphology of scaffolds prepared by electrospinning significantly affects the biological behavior of bone marrow mesenchymal stem cells （BMSC）， such as fiber diameter， fiber arrangement， pore size and porosity. This review focused on the effect of the micromorphology of electrospinning scaffold materials on the biological behavior of BMSC， in order to provide reference for the design of physical factors of electrospinning scaffold materials.

Key words: 　Electrostatic spinning, 　Micro-morphology, 　Bone marrow mesenchymal stem cells