Objective To evaluate the clinical efficacy and safety of autologous fat granule transplantation in facial contouring.Methods From May 2013 to May 2016,70 patients treated with autologous fat granule transplantation were selected.Subcutaneous fat was injected into facial regions after centrifugation and purification process through subcutaneous tumescent liposuction.The clinical data,complications and the satisfaction of the patients were analyzed retrospectively.Results All operations were successfully completed;After 6 months of postoperative follow-up,no infection,fat liquefaction,necrosis,induration?and embolism were observed;The satisfaction rate of the patients were 94.85%and 97.94%at 1 month and 6 month after operation respectively.Conclusion Autologous fat granule transplantation is effective in facial contouring with high success rate and low complication rate.It is worthy of clinical promotion.