Review

Advances of Sirolimus in the Treatment of Vascular Malformation

Expand

Received date: 2019-03-07

  Revised date: 2019-04-23

  Online published: 2019-08-20

Abstract

Vascular malformation is a group of developmental malformations originating from blood vessels and/or lymphatics that can invade multiple organs and systems, causing pain, disfigurement, dysfunction, and even death. At present, the treatment methods of vascular malformation are various, but the effect is not satisfactory. Sirolimus, a mammalian target protein receptor inhibitor of rapamycin, has been shown to be effective in the treatment of vascular malformations. In this paper, the mechanism, application, effect and possible side effects of sirolimus in treating vascular malformation were reviewed, in order to provide a new idea for treating such diseases.

Cite this article

SUN Buhao . Advances of Sirolimus in the Treatment of Vascular Malformation[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2019 , 15(4) : 263 -265 . DOI: 10.3969/j.issn.1673-0364.2019.04.012

Options
Outlines

/