Objective To explore the effect of three surgical methods for the treatment of moderate and severe ble-pharoptosis. Methods From May 2015 to April 2018, ninety patients(120 eyes) with congenital moderate and severe ble-pharoptosis were selected. According to the principle of random grouping, the patients were randomly divided into 3 groups:group A, B and C. Patients in group A were treated by frontal muscle fascia suspension, patients in group B were treated by traditional levator shortening, and patients in group C were treated with levator palpebrae muscle shortening and fascial sheath suspension. After 6 months of treatment, the differences of therapeutic effect, blepharoptosis correction rate, cosmetic effect, surgical indexes and complications were observed. Results The total effective rate and the correction rate of group C were both significantly higher than those of group A and group B(P0.05). Conclusion Combined with fascial sheath suspension in the treatment of moderate and severe ptosis, it can effectively improve the height of palpebral fissure with high safety and significant therapeutic and cosmetic effects.