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The Significance of Epithelium-to-Mesenchymal Transition in Keloid Treatment

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Online published: 2020-07-23

Abstract

Keloid scar is a fibrogenesis tumor-like disease featured by invasion to the surrounding skin. Epithelium-to-mesenchymal transition (EMT) is a process which leads to the loss of epithelial cell polarity and cell-cell adhesion. Through the process of EMT, epithelial cells acquire migratory and invasive behavior and are thus able to transform into mesenchymal cells. EMT has a high clinical significance towards keloid treatment.

Cite this article

ZHANG Mingzi,WANG Xiaojun . The Significance of Epithelium-to-Mesenchymal Transition in Keloid Treatment[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2017 , 13(3) : 121 -122 . DOI: 10.3969/j.issn.1673-0364.2017.03.001

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