Objective To explore an effective method for treating axillary osmidrosis and decreasing complications after operation.Methods A 2-3 cm long skin incision was designed in the middle and lower of the axillary crease and the undermine scope of tissue was over 1 cm out of the axillary hair growth area.The sweat glands and subcutaneous tissue attached to the dermis were removed manually with scissors and curettage and the skin was repaired into full-thick skin flap.After operation,the skin was anchored to the subcutaneous tissues with more than 10 sutures using interrupted suturing technique.8-shaped compression dressing was wrapped to each axilla.Results All 208 patients were followed up for 6 to 12 months.Malodor elimination was totally treated in 200 of 208 (98％),fair in 8 (2％) and the efficient rate was 100％.Recurrence of axillary osmidrosis occurred in 3 patients and 2 cases were cured by re-operation.No subcutaneous hematoma,effusion,infection and skin necrosis happened after operation and the incision healed well.No obvious obstacle in activity was observed and all patients recovered well.Conclusion Shaving together with curettage for removing the apocrine and eccrine glands and interrupted suturing technique to anchor skin has the advantages of effective resection,high successful rate and fewer complications.