Objective To investigate the effectiveness of a novel radiofrequency system:focused-radiofrequency system on facial rejuvenation. Methods From October 2015 to February 2016, 20 patients with facial aging skin accepted the focused-radiofrequency therapy. Standard photographs and digitized measurement were taken before the therapy and 3 months after the therapy. The length of the bilateral nasolabial fold and the angle of bilateral nasolabial fold were measured. Results Compared with pre-treatment, the length of bilateral nasolabial fold 3 months after the therapy was significantly reduced (P0.05). Conclusion Focused-radiofrequency is an effective treatment for facial rejuvenation, especially in improving the length of nasolabial fold.