Objective To explore the efficiency of digital three-dimensional？molding technology for the repair of the complex maxillofacial depression. Methods From January 2014 to May 2016, 12 cases with complex maxillofacial depression were treated using digital three-dimensional？molding technology. The surgical methods, timing and prognosis were analyzed retrospectively. Results Using the digital three-dimensional molding technology, the conformity has been greatly improved. 12 patients all regained their original shapes of maxillofacial bones. At the same time, the average operation time reduced by two hours. Up to now, no serious complications were observed, like shift, leakage or rejection of the complement. Conclusion Repairing maxillofacial depression with the technique of three-dimension shaping can obviously improve the conformity and reduce operation time and risk, which is worth popularization and application.