How to keep the finn lower facial contour along with the gradually aging process is the major point that Asian women focus on. They are seeking for an minimally invasive and less risky approach, compared with the traditional surgery. The past two decades has seen the botulinum toxin type A （BTX-A） injection as a relatively noninvasive, conservative, and reversible preferred method for women who seek for beauty. The application of BTX-A in upper and mid face has been widely accepted. The use of BTX-A in the lower face has been attracting more and more attention for harmonious lineament. In this paper, the research progress of Botulinum toxin type A for lower facial rejuvenation was reviewed.