Objective To evaluate the clinical efficacy of virtual osteotomy and bone graft association with digital techniques in treating patient with middle facial cleft and nasal malformation. Methods The patient with middle facial cleft and nasal malformation was included in the study. After CT scanning, the 3D image was analyzed by Mimics 10.01 and virtual osteotomy was performed. The range of osteotomy, direction and distance of bone block movement were all preplanned. Results No serious complication was observed and the patient was satisfied with the results. Conclusion Though using digital technology, the effects of operation could be improved according to an accurate and controllable preoperation plan .