Journal of Tissue Engineering and Reconstructive Surgery >

2011 , Vol. 7 >Issue 1: 45 - 47

DOI: https://doi.org/10.3969/j.issn.1673-0364.2011.01.013

Original article

Endogenous Inhibitor of Nitric Oxide Synthase and Reprogramming Functional Cardiac Stem Cells

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  • Department of Cardiovascular and Thoracic Surgery,Shanghai East Hospital,Tongji University,Shanghai 200120,China.

Online published: 2020-07-23

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Abstract

Stem cells regenerative medicine plays an important role in the repair of organ tissue and regeneration.By now,reprogramming of somatic cells through the exogenous genes is the most hopeful way to get transplant cells.Microenvironment is the most important factor in the survival,immigration,and differentiation of transplanted cells.Endogenous inhibitor of nitric oxide synthase system(ADMA/DDAH pathway) may plays a key role in regulating angiogenesis,inducing differentiation of muscle cells and promoting muscle generation by the DDAH/ADMA pathway regulation.

Key words： Asymmetric dimethylarginine; Reprogramming; Functional cardiomyocytes; Fibroblast

Cite this article

WANG Jinyi,FAN Huimin,LIU Zhongmin . Endogenous Inhibitor of Nitric Oxide Synthase and Reprogramming Functional Cardiac Stem Cells[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2011 , 7(1) : 45 -47 . DOI: 10.3969/j.issn.1673-0364.2011.01.013

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