Objective To explore the clinical results of applying free anterolateral thigh perforator flap to repair skin and soft tissue defects in anterior tibial.Methods Fourteen cases of skin and soft tissue defect of anterior tibial with exposed bone using free anterolateral thigh perforator flap.The size of the flaps ranged between 14 cm × 6 cm and 23 cm × 12 cm.The donor area was directly closed or full-thickness skin grafting.Results All flaps survived in 14 cases.All patients were available for follow-up 3-24 months.The repaired tissue was in good match with surrounding tissue.Eight cases achieved protective sensation.Conclusion Anterolateral thigh perforator flap could be used to repair the soft tissue defects of anterior tibial and obtain good colour,contour.