Journal of Tissue Engineering and Reconstructive Surgery >

2009 , Vol. 5 >Issue 1: 29 - 31

DOI: https://doi.org/10.3969/j.issn.1673-0364.2009.01.008

Original article

Skin Sensitization Test of Silk Fibroin-based Nerve Guidance Conduit

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  • Jiangsu Key Laboratory of Neuroregeneration;Nantong University;Nangtong 226001;China.;

Online published: 2020-07-23

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Abstract

Objective To study the sensitization of silk fibroin-based nerve guidance conduits (SF-NGCs) in vitro. Methods According to ISO 10993-10:1995 standard, maximization test was conducted in guinea pig. The skin sensitization reactions, including erythema and oedema, induced by SF-NGCs, normal saline and formalin solution were observed and scored respectively at 24, 48 and 72 h exposure of the infusion of the materials. The allergenic rates and mean response score were calculated. Results The allergenic rates a...

Key words： Silk Fibroin-based Nerve Guidance Conduit; Biocompatibility; Skin Sensitization Test

Cite this article

YAN Xiaoli,ZHAO Yahong,ZHAO Weijia,YANG Yumin . Skin Sensitization Test of Silk Fibroin-based Nerve Guidance Conduit[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009 , 5(1) : 29 -31 . DOI: 10.3969/j.issn.1673-0364.2009.01.008

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