Journal of Tissue Engineering and Reconstructive Surgery >

2009 , Vol. 5 >Issue 3: 134 - 137

DOI: https://doi.org/10.3969/j.issn.1673-0364.2009.06.005

Original article

Experimental Study on Tissue Engineered Blood Vessel with Bioreactor

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  • 1 Department of Plastic and Reconstructive Surgery;The Ninth People s Hospital;Shanghai Jiaotong University School of Medicine;Shanghai 200011;China.2 Shanghai Tissue Engineering Research and Development Center;Shanghai 200235;China.;

Online published: 2020-07-23

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Abstract

Objective To investigate the feasibility of constructing tissue engineered blood vessels with bioreactor.Methods Cell-PGA(polyglycolic acid) complex was constructed by seeding smooth muscle cells(SMCs) isolated from canine carotid artery on PGA unwoven fibers.The cell-PGA complex was cultured in a bioreactor(pulse rate:75 /min,radical distension<5%).Eight weeks after culture in vitro,Endothelial cells(ECs) isolated from canine carotid vein were seeded on PGA and cultured for another 5 days.The control gr...

Key words： Tissue engineering; Bioreactor; Blood vessel; Reconstruction

Cite this article

XU Zhicheng,ZHANG Wenjie,LI Hong,ZHOU Guangdong,CUI Lei,LIU Wei,CAO Yilin . Experimental Study on Tissue Engineered Blood Vessel with Bioreactor[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009 , 5(3) : 134 -137 . DOI: 10.3969/j.issn.1673-0364.2009.06.005

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