Journal of Tissue Engineering and Reconstructive Surgery >

2009 , Vol. 5 >Issue 4: 199 - 207

DOI: https://doi.org/10.3969/j.issn.1673-0364.2009.08.005

Original article

Experimental Study of Interaction between SERP 2 and Periostin in the Formation of Keloid

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  • Department of Plastic Surgery and Institute of Burn;Southwest Hospital;Affiliated Third Military Medical University;Chongqing 400038;China.;

Online published: 2020-07-23

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Abstract

Objective To investigate the interaction between Periostin (osteoblast-specific factor 2) and SFRP 2 (Secreted frizzled-related protein 2) in the formation of keloid. Methods HA-tagged fusion protein (HA- Periostin) expression vector was constructed, identified and transfected into human embryo kidney 293 (HEK293) cells alone or with Myc-tagged fusion protein (Myc-SFRP 2) expression vector pMCV-Myc-SFRP 2. The interaction between SFRP 2 and Periostin was detected by pull-down technique. Results Double restr...

Key words： Secreted frizzled-related protein 2; Periostin; Interaction

Cite this article

WANG Zhenxiang,YUAN Shunzong,TAO Xi,LI Shirong,WU Jun . Experimental Study of Interaction between SERP 2 and Periostin in the Formation of Keloid[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009 , 5(4) : 199 -207 . DOI: 10.3969/j.issn.1673-0364.2009.08.005

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