The communication and cooperation between teachers and students in classroom is promoted by the multiple interactive English teaching mode based on the Constructivism theory. Through the diverse aspects of the multiple interactive English teaching mode analysis, it is found that, as a party involved in teaching activities, teachers are lack of flexibility of their ideas and forms of organization, lack of corpus input and output, and apply the unreasonable evaluation mechanism, which leads to the poor teaching effectiveness. Teachers preconstruct corpus before classroom, optimize language learning environment, reasonably arrange teaching segments, flexibly organize teaching activities, cleverly pass on teaching contents, improve students’ interest in learning. Students actively participate in teaching activities and digest knowledge after school. Effectiveness of the multiple interactive English teaching mode can be enhanced as well as the learning capacity and enthusiasm of students. Meanwhile, students’ learning motivation is stimulated by appropriate evaluation of teachers. Positive interaction between teachers and students and among students is achieved.