As an emerging meta-discipline in translation studies, Transknowletology has developed through three years of theoretical and practical exploration. This study examines its disciplinary institutionalization by analyzing 2022-2025 literature from China National Knowledge Infrastructure (CNKI) using academic historiography and descriptive analysis methods. Key findings indicate: (1) Theoretically, an ontological framework emphasizing “theoretical construction” has been established, enriched through interdisciplinary engagement with philosophical epistemology and sociology of knowledge; (2) Practically, research frontiers have expanded beyond humanistic translation to form specialized paradigms in science, medicine, and law. However, critical gaps persist: insufficient empirical research in natural and social sciences and lack of research on translation historiography and knowledge genealogy. To address these, future directions should focus on: (1) enhancing empirical studies in natural science, social science and interdisciplinary translation. (2) advancing knowledge archaeology through disciplinary translation histories and genealogical mappings to clarify knowledge’s centrality in translational evolution. This article provides a foundational reference for Transknowletology’s disciplinary positioning and strategic development.