目的：调查及探讨接受体外受精-胚胎移植（in vitro fertilization-embryo transfer, IVF-ET）女性的生育生活质量及其影响因素。 方法：采用简单随机抽样的方法,选取2018年12月至2019年6月期间在上海交通大学医学院附属瑞金医院生殖医学中心进行IVF-ET的女性236例,采用一般资料调查表、生育生活质量量表、领悟社会支持量表、焦虑自评量表、抑郁自评量表对其进行问卷调查,并采用广义线性模型,分析、明确影响其生育生活质量的独立因素。 结果：本研究接受IVF-ET女性的其生育生活质量总分为（64.6±13.12）分。广义线性模型分析显示,较高的不孕年限（β=-4.876 9,P<0.001）、较重的经济困难（β=-7.212 1,P<0.001）、男方因素导致的不孕（β=-3.652 3,P=0.038）、较多的治疗周期（β=-6.825 2,P<0.001）、较严重的抑郁（β=-0.441 3,P<0.001）与生育生活质量呈独立负相关;而居住在城镇（P=0.018 6）、更高的月收入（P=0.018 1）、较好的家庭支持（P<0.001）则与生育生活质量呈独立正相关。 结论：接受IVF-ET女性的生育生活质量显著偏低,而居住地、月收入及社会支持显著影响其生育生活质量。

Objective: To investigate the fertility quality of life (Ferti QoL) of female patients undergoing in vitro fertilization and embryo transfer (IVF-ET), and to explore the related influenced factors. Methods: The random sampling has been conducted to enroll subjects, and questionnaires (General Information, Fertility Quality of Life, Perceived Social Support Scale, Self-Rating Anxiety Scale and Self-rating Depression Scale) were performed in patients undergoing IVF-ET at Reproductive Medicine Center of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine during December 2018 to June 2019. Results: A total of 236 IVF-ET patients were recruited in the study, and the total score of Ferti QoL was (64.6±13.12). Multiple linear regression analysis indicated that longer years of infertility(β=-4.8769, P<0.001), more financial difficulties (β=-7.2121, P<0.001), male factor-infertility (β=-3.6523, P=0.038), more IVF-EF cycles (β=-6.8252, P<0.001) and heavy depression (β=-0.4413, P<0.001) were independent factors for low FetiQoL. While living in a town (P=0.0186), having high monthly income (P=0.0181) and high degree of family support (P<0.001) were independently positively correlated with FertiQoL. Conclusions: The female undergoing IVF-EF have a significantly lower FertiQoL score, and while residence, monthly income, and social support are significantly associated with FertiQoL.