目的: 分析肝硬化食管静脉曲张内镜下皮圈结扎术(endoscopic varix ligation,EVL)对门静脉高压性胃病(portal hypertensive gastropathy,PHG)的影响。方法: 回顾性分析63例肝硬化PHG患者,其中35例食管静脉曲张行EVL术治疗者为治疗组,28例未行内镜下治疗者为对照组。8周后复查胃镜,观察患者有无PHG加重改变。结果: EVL治疗组中发生PHG加重变者占74.28%(26/35),对照组中发生PHG加重变者占10.71%(3/28)。经χ2检验,两者间差异有统计学意义(P<0.01)。结论: 食管静脉曲张的EVL治疗可能是PHG发生和加重的重要危险因素。
Objective: To investigates the effect of endoscopic variceal ligation (EVL) on portal hypertensive gastropathy (PHG) in liver cirrhosis patients. Methods: Sixty-three liver cirrhosis patients with PHG were divided into 2 groups: patients with EVL treatment (35 cases) and control groups without endoscopic therapy (28 cases). Eight weeks after therapy, endoscopy was performed to determine the aggravation of PHG. Results: Increased severity of PHG was seen in 26 cases (74.28%, 26/35) of treated group, while only 3 (10.71%) in the control group showed increase of severity (P<0.01). Conclusions: EVL of esophageal varices might be an important risk factor for the development and aggravation of PHG in liver cirrhosis patients.
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