诊断学理论与实践 ›› 2016, Vol. 15 ›› Issue (05): 468-471.doi: 10.16150/j.1671-2870.2016.05.007

• 论著 • 上一篇    下一篇

肝硬化食管静脉曲张内镜下皮圈结扎术对门静脉高压性胃病的影响及研究

王晓瑜1, 徐艳1, 王利兵1, 吴云林2, 陈平2, 张国华1   

  1. 1.南京中医药大学附属张家港市中医医院消化内科,江苏 张家港 215600;
    2.上海交通大学医学院附属瑞金医院北院消化内科,上海 201821
  • 收稿日期:2016-10-08 出版日期:2016-10-25 发布日期:2022-07-27
  • 通讯作者: 张国华 E-mail: xiaou0503@163.com

The effect of endoscopic variceal ligation on portal hypertensive gastropathy in liver cirrhosis patients

WANG Xiaoyu1, XU Yan1, WANG Libing1, WU Yunlin2, CHEN Ping2, ZHANG Guohua1   

  1. 1. Department of Gastroenterology, Zhangjiagang Hospital of Traditional Chinese Medicine, Affiliated to Nanjing University of Traditional Chinese Medicine, Jiangsu Zhangjiagang 215600, China;
    2. Department of Gastroenterology, Ruijin Hospital North, Shanghai Jiao Tong University School of Medicine, Shanghai 201821, China
  • Received:2016-10-08 Online:2016-10-25 Published:2022-07-27

摘要: 目的: 分析肝硬化食管静脉曲张内镜下皮圈结扎术(endoscopic varix ligation,EVL)对门静脉高压性胃病(portal hypertensive gastropathy,PHG)的影响。方法: 回顾性分析63例肝硬化PHG患者,其中35例食管静脉曲张行EVL术治疗者为治疗组,28例未行内镜下治疗者为对照组。8周后复查胃镜,观察患者有无PHG加重改变。结果: EVL治疗组中发生PHG加重变者占74.28%(26/35),对照组中发生PHG加重变者占10.71%(3/28)。经χ2检验,两者间差异有统计学意义(P<0.01)。结论: 食管静脉曲张的EVL治疗可能是PHG发生和加重的重要危险因素。

关键词: 肝硬化, 食管静脉曲张皮圈结扎术, 门静脉高压性胃病

Abstract: Objective: To investigates the effect of endoscopic variceal ligation (EVL) on portal hypertensive gastropathy (PHG) in liver cirrhosis patients. Methods: Sixty-three liver cirrhosis patients with PHG were divided into 2 groups: patients with EVL treatment (35 cases) and control groups without endoscopic therapy (28 cases). Eight weeks after therapy, endoscopy was performed to determine the aggravation of PHG. Results: Increased severity of PHG was seen in 26 cases (74.28%, 26/35) of treated group, while only 3 (10.71%) in the control group showed increase of severity (P<0.01). Conclusions: EVL of esophageal varices might be an important risk factor for the development and aggravation of PHG in liver cirrhosis patients.

Key words: Liver cirrhosis, Esophageal variceal ligation, Portal hypertensive gastropathy

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