Objective: To investigate the relationship between resting heart rate and diabetes mellitus in a community-based study among middle-aged and elderly population. Methods: A survey of 4 012 subjects aged 40 years or older in Songnan community of Shanghai Baoshan District was performed using cluster sampling. All the individuals recruited underwent questionnaire interview and anthropometric measurements. Blood samples were collected to measure biochemical indices, including fasting blood glucose, 2 h postprandial blood glucose and lipid profiles. Diabetes mellitus was diagnosed according to the World Health Organization criteria in 2006. Participants were divided into 5 groups by resting heart rate quintiles. Logistic regression analysis was used to analyze the risk of diabetes among people with different resting heart rate levels. Results: The prevalence of diabetes was increased from quintile 1 to quintile 5: 22.94%,27.77%,31.94%,37.21%,46.76% (P<0.0001). Resting heart rate level was positively correlated with fasting blood glucose, 2-h postprandial blood glucose, and homeostasis model assessment for insulin resistance (all P<0.001). After adjustment for other conventional risk factors, those in the quintile 5 group had 1.77 folds higher risk of diabetes mellitus when compared with individuals in the quintile 1 group [odds ratio (OR)=2.77, 95% confidence interval (CI): 2.18-3.51]. Conclusions: In the middle-aged and elderly population, a high-normal resting heart rate level is associated with an increased risk of diabetes mellitus, suggesting that we should monitor the participants who have high level of heart rate.
WU Xueyan, MA Lina, CHENG Di, DU Rui, XU Yu, XU Min, LU Jieli, CHEN Yuhong, BI Yufang, WANG Weiqing, GAO Jinli, QIAN Xiaozhong
. Association between resting heart rate and diabetes mellitus among a middle-aged and elderly community population[J]. Journal of Diagnostics Concepts & Practice, 2018
, 17(01)
: 45
-50
.
DOI: 10.16150/j.1671-2870.2018.01.008
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