Journal of Diagnostics Concepts & Practice >

2022 , Vol. 21 >Issue 01: 41 - 45

DOI: https://doi.org/10.16150/j.1671-2870.2022.01.009

Original articles

Effect of game-based EEG neurofeedback training on improvement of cognitive function

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  • 1. Department of Neurology, First Hospital, Hebei Medical University, Shijiazhuang Hebei, 050031
    2. Brain Aging and Cognitive Neuroscience Key Laboratory of Hebei Province, Shijiazhuang, Hebei 050031
    3. Qinhuangdao Huisianpu Medical System Co., Ltd., Qinhuangdao Hebei, 066000, China

Online published: 2022-02-25

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Abstract

Objective: To observe the effect of game-based EEG neurofeedback system on improvement of cognitive function in the patients with cognitive impairment. Methods: Fifty-two patients with cognitive impairment, mainly memory decline, were included, and the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment Scale (MoCA) and Alzheimer′s Disease Assessment Scale-Cognitive section(ADAS-cog) were conducted in the patients to evaluate cognitive impairment. Five days later, each patient was given 30-min EEG neural feedback training, once a day for 10 consecutive days. The EEG was detected before and after training, and MMSE, MoCA and ADAS-cog scores were also evaluated after training. Results: The scores of MMSE, MoCA and ADAS-cog scales after training were all higher(26.06±2.95, 21.88±3.94, 12.15±5.15) than those before training (23.10±2.82, 18.63±4.10, 14.76±5.30) (P<0.05). Before training, the scores of memory on MMSE, MoCA and ADAS-cog scales were 1.55±0.77, 1.33±1.28, 4.35±1.11, respectively, while the above scores increased to 2.16±0.80, 2.29±1.34, 3.93±1.30(P<0.001) after training. The EEG after training showed that the complexity of EEG was improved than that before training, mainly in the left frontal lobe. Conclusions: The game-based EEG neurofeedback system training can significantly improve cognitive function and EEG complexity in the left prefrontal lobe.

Key words： EEG neurofeedback; Memory decline; Cognitive impairment

Cite this article

MA Shaochen, GUO Xin, WANG Mingwei, WANG Huijun, YU Qijun, SU Wenyue, WANG Hualong, MA Qinying . Effect of game-based EEG neurofeedback training on improvement of cognitive function[J]. Journal of Diagnostics Concepts & Practice, 2022 , 21(01) : 41 -45 . DOI: 10.16150/j.1671-2870.2022.01.009

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