Objective: To compare the performance difference on image quality between sinogram-affirmed iterative reconstruction (SAFIRE) and filtered back projection （FBP）in low-dose lung CT screening. Methods: A total of 304 patients receiving annual low-dose lung CT screening were examined by a dual-source CT system at 120 kV with reference tube current of 40 mA·s. Six image serials were reconstructed, including one dataset of FBP and five datasets of SAFIRE with different reconstruction strengths from 1 to 5 (S1 to S5). Image noise and subjective scores of image noise were recorded. Images artifacts and overall image quality were also assessed by two radiologists. Results: The mean weight and the body mass index of patients were （66.3±12.8） kg and 23.4±3.2, respectively. The mean dose-length product was (95.2±30.6） mGy·cm, and the effective dose was （1.6±0.5） mSv. The observation agreement for image noise grade, artifact grade and the overall image quality was in good consistency (r=0.785, 0.595 and 0.512). Among the overall six datasets, both the scores of measured mean objective image noise and the subjective image noise of FBP were the highest, and the image noise decreased with the increasing of SAFIRE reconstruction strength. The datasets of S3 obtained were the highest quality scores for image. Conclusions: Compared with FBP, SAFIRE reconstruction may significantly improve image quality in low-dose lung CT screening and SAFIRE with reconstruction strength 3 is a pertinent choice for low-dose lung CT.
WU Meng xiong, CAO Qiqi, YANG Wenjie, YAN Fuhua, YAN Ling
. Application of sinogram-affirmed iterative reconstruction technique in low-dose lung CT screening[J]. Journal of Diagnostics Concepts & Practice, 2017
, 16(01)
: 104
-108
.
DOI: 10.16150/j.1671-2870.2017.01.020
[1] 任法云, 付克广. 低剂量CT在肺结节筛查中的临床应用[J]. 中国医学计算机成像杂志,2014,20(5):389-393.
[2] 刘士远, 于红. 积极推进胸部低剂量CT扫描的临床应用[J]. 中华放射学杂志,2010,44(1):6-7.
[3] 陈疆红, 贺文, 赵丽琴, 等. 适应性统计迭代重建技术降低胸部低剂量CT图像噪声的效果[J]. 中国医学影像技术,2011,27(12):2398-2402.
[4] National Lung Screening Trial Research Team, Aberle DR, Berg CD, et al. The National Lung Screening Trial: overview and study design[J]. Radiology,2011,258(1):243-253.
[5] Larke FJ, Kruger RL, Cagnon CH, et al.Estimated radia-tion dose associated with low-dose chest CT of average-size participants in the National Lung Screening Trial[J]. Am J Roentgenol,2011,197(5):1165-1169.
[6] 王芳, 高剑波, 刘杰, 等. 正弦图确定迭代重建技术在降低胸部扫描剂量中的应用[J]. 中国医学影像技术,2012,28(11):2087-2089.
[7] Moscariello A, Takx RA, Schoepf UJ, et al.Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique-comparison with traditio-nal filtered back projection[J]. Eur Radiol,2011,21(10):2130-2138.
[8] Wang R, Schoepf UJ, Wu R, et al.Image quality and radiation dose of low dose coronary CT angiography in obese patients: sinogram affirmed iterative reconstruction versus filtered back projection[J]. Eur J Radiol,2012, 81(11):3141-3145.
[9] 王敏杰, 王培军, 田建明, 等. 胸部低剂量CT扫描技术的应用价值[J]. 中华放射学杂志,2002,36(8):761-762.
[10] Pontana F, Pagniez J, Flohr T, et al.Chest computed tomography using iterative reconstruction vs filtered back projection (Part 1): Evaluation of image noise reduction in 32 patients[J]. Eur Radiol,2011,21(3):627-635.
[11] Prakash P, Kalra MK, Digumarthy SR, et al.Radiation dose reduction with chest computed tomography using adaptive statistical iterative reconstruction technique: initial experience[J]. J Comput Assist Tomogr,2010,34(1):40-45.
[12] Lee TY, Chhem RK.Impact of new technologies on dose reduction in CT[J]. Eur J Radiol,2010,76(1):28-35.
[13] Prasad SR, Wittram C, Shepard JA, et al.Standard-dose and 50%-reduced-dose chest CT: comparing the effect on image quality[J]. Am J Roentgenol,2002,179(2):461-465.
[14] Singh S, Kalra MK, Gilman MD, et al.Adaptive statistical iterative reconstruction technique for radiation dose reduction in chest CT: a pilot study[J]. Radiology,2011, 259(2):565-573.
