桥本甲状腺炎的研究进展
Research progress of Hashimoto thyroiditis
Received date: 2024-06-20
Online published: 2024-11-11
桥本甲状腺炎(Hashimoto thyroiditis，HT)是很常见的器官性自身免疫性甲状腺疾病，发病率逐年上升，在临床中不仅会导致甲状腺功能减退，还发现其与多种免疫性疾病、内分泌疾病、风湿性疾病及甲状腺癌之间存在诸多联系。虽然确切的病因尚未完全阐明，治疗的主流仍是基于管理与替代治疗甲状腺功能减退，但随着研究的进一步深入，更多的临床变异类型被逐步发现，越来越多的因素被发现与HT的发病相关，治疗方法也有新发现。本文就HT的临床表现、病理特征和诊断、发病机制、与其他疾病的关系及治疗等方面的研究进展作一综述。
关键词： 桥本甲状腺炎; 自身免疫; 甲状腺功能减退; 甲状腺自身免疫性疾病
田利民 , 冯婧 . 桥本甲状腺炎的研究进展[J]. 内科理论与实践, 2024 , 19(04) : 217 -223 . DOI: 10.16138/j.1673-6087.2024.04.01
Hashimoto thyroiditis (HT) is a very common organic autoimmune thyroid disease, and its incidence is increasing year by year. It not only causes hypothyroidism in clinical practice, but also has many connections with a variety of immune diseases, endocrine diseases, rheumatic diseases and thyroid cancer. Although the exact etiology of HT has not been fully clarified, the mainstream treatment is still based on management and alternative treatment of hypothyroidism. However, as the research further deepens, more clinical variants have been gradually discovered, more and more factors have been found to be related to the onset of HT, and new discoveries have been made in treatment methods. This article reviews the research progress on clinical manifestations, pathological features, diagnosis, pathogenesis, relationship with other diseases and treatment of HT.
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