多模态磁共振在系统性红斑狼疮早期脑损害识别中的应用
收稿日期: 2024-11-06
网络出版日期: 2025-03-11
基金资助
国家自然科学基金(32270947);国家自然科学基金(81760296);云南省卫生健康委员会医学领军人才培养项目(L-2019004);云南省“万人计划”专项培养计划(YNWR-MY-2018-040);云南省卫生健康委临床医学中心建设项目(ZX2019-03-02);云南省科技计划项目(2018ZF016)
Application of multimodal magnetic resonance in identification of early brain damage in systemic lupus erythematosus
Received date: 2024-11-06
Online published: 2025-03-11
随着全球范围内自身免疫性疾病发病率的不断上升，系统性红斑狼疮(systemic lupus erythematosus, SLE)作为一种典型的自身免疫性疾病，其导致的脑损害日益受到关注。SLE患者脑损害发病率高且预后不良，而早期准确识别脑损害对及时干预和治疗至关重要。磁共振成像技术作为一种非侵入性影像学检查方法，可提供多模态、高分辨率的丰富数据，在SLE早期脑损害的定量研究和临床诊断评估中具有重要应用价值。本文旨在探讨多模态磁共振技术在SLE早期脑损害的机制研究和临床应用中的意义，以期为SLE患者脑损害的早期干预和治疗提供更有力的支持。
杨一帆 , 张国芳 , 徐健 . 多模态磁共振在系统性红斑狼疮早期脑损害识别中的应用[J]. 内科理论与实践, 2024 , 19(06) : 372 -378 . DOI: 10.16138/j.1673-6087.2024.06.04
With the growing number of autoimmune disorders globally, systemic lupus erythematosus (SLE), a common autoimmune disease, has received increased attention for its associated brain damage. Brain damage is common in SLE patients, and the prognosis is poor. Accurate detection of early brain damage is critical for timely diagnosis and therapy. Magnetic resonance imaging, as a non-invasive imaging technology, can provide multi-modal, high-resolution and rich data, which has good application value for quantitative research, clinical diagnosis and evaluation of early SLE brain damage. The aim of the article is to explore the role of multimodal magnetic resonance in the mechanism research and clinical diagnosis of early brain damage in SLE patients, as well as to give additional support for early intervention and treatment of brain damage.
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