内科理论与实践

内科理论与实践 >

2025 , Vol. 20 >Issue 01: 76 - 80

DOI: https://doi.org/10.16138/j.1673-6087.2025.01.16

综述

虎杖苷在消化系统疾病治疗中的研究进展

  • 吴超 ,
  • 庄蕾 ,
  • 马君俊 ,
  • 何子锐 ,
  • 孙永顺
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  • 1.上海交通大学医学院附属瑞金医院 a.普外科 上海市微创外科临床医学中心；b.麻醉科，上海 200025
    2.上海中医药大学附属上海市中医医院脾胃病科，上海 200071

收稿日期: 2024-10-29

  网络出版日期: 2025-04-30

基金资助

国家自然科学基金项目(82103356);国家自然科学基金项目(82174128);国家自然科学基金项目(81874402);上海市中医医院未来计划项目(WLJH2021ZY-MZY032);上海市中医医院未来计划项目(WL-HBBD-2021003K);湖北陈孝平科技发展基金会资助项目(CXPJJH12000001-2020329)

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Research progress of polydatin in treatment of digestive system diseases

  • WU Chao ,
  • ZHUANG Lei ,
  • MA Junjun ,
  • HE Zirui ,
  • SUN Yongshun
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  • 1a. Department of General Surgery, Shanghai Clinical Center for Minimally Invasive Surgery; b. Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China
    2. Department of Gastroenterology,Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated with Shanghai University of Traditional Chinese Medicine, Shanghai 200071,China

Received date: 2024-10-29

  Online published: 2025-04-30

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摘要

虎杖苷是从传统中药材虎杖中提取的主要活性成分，具有抗炎、抗氧化和调节细胞凋亡等多种药理作用。其在肝病、炎症性肠病等消化系统疾病治疗中的应用研究逐渐受到关注。本文综述虎杖苷在消化系统（肝胆胰及胃肠道）良恶性疾病中的治疗进展，分析其潜在作用机制，以期为虎杖苷干预消化系统疾病的深入研究提供新思路。

关键词： 虎杖苷; 消化系统; 虎杖

本文引用格式

吴超 , 庄蕾 , 马君俊 , 何子锐 , 孙永顺 . 虎杖苷在消化系统疾病治疗中的研究进展[J]. 内科理论与实践, 2025 , 20(01) : 76 -80 . DOI: 10.16138/j.1673-6087.2025.01.16

Abstract

Polydatin is the main active ingredient extracted from the traditional Chinese herbal medicine Polygonum cuspidatum, which has multiple pharmacological effects such as anti-inflammation, antioxidant and apoptosis regulation. Its application in the treatment of liver disease, inflammatory bowel disease and other digestive system diseases has gradually attracted attention. This article reviews therapeutic progress of polydatin in benign and malignant diseases of the digestive system (liver, gallbladder, pancreas and gastrointestinal tract), analyzes the potential mechanism of polydatin in the treatment of digestive disorders. We hope to provide new ideas for in-depth research on application of polydatin in digestive disorders.

Key words： Polydatin; Digestive system; Polygonum cuspidatum

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