目的：探讨梗阻性肥厚型心肌病患者行左心室流出道疏通术后1年心电图及心脏超声相关变化及特点。方法：入选2018年1月1日至12月31日期间在上海交通大学医学院附属瑞金医院明确诊断为梗阻性肥厚型心肌病并接受左心室流出道疏通术的患者共38例，收集临床资料及术前、术后1年的心电图和心脏超声结果，进行对比分析，总结其相关变化及特点。结果：手术后1年随访心电图诊断为左心室肥厚的比例较手术前显著下降（52.6%比12.9%，P<0.01），诊断为完全性左束支传导阻滞比例显著上升（2.6%比58.1%，P<0.01）。术后1年随访心脏超声显示患者左室射血分数较术前降低（68.50%±4.11%比63.87%±4.00%，P<0.01）。术后1年有完全性左束支传导阻滞患者左室射血分数较术前降低（69.39%±5.29%比63.40%±4.15%，P<0.01），无完全性左束支传导阻滞患者左室射血分数手术前后无统计学差异（67.46%±2.96%比64.83%±4.20%，P=0.082）。结论：左心室流出道疏通术可有效降低梗阻性肥厚性心肌病患者的左心室肥厚比例，缓解流出道梗阻，但术后有完全性左束支阻滞的患者左室射血分数有降低趋势。

Objective To investigate the changes and characteristics of electrocardiogram and echocardiography in patients with hypertrophic obstructive cardiomyopathy at 1 year after left ventricular outflow tract dredging.Methods To investigate patients diagnosed with hypertrophic obstructive cardiomyopathy who underwent left ventricular outflow tract dredging surgery in Ruijin Hospital, Shanghai Jiao Tong University School of Medicine from January 1 to December 31 in 2018. A total of 38 cases were enrolled, the clinical features, electrocardiogram and echocardiography data before, 1 year after surgery were collected for comparative analysis and summarizations.Results There were significant statistical differences in the proportion of left ventricular hypertrophy (LVH) and complete left bundle branch block (CLBBB) on electrocardiogram (52.6% vs 12.9%, P<0.01) and (2.6% vs 58.1%, P<0.01), respectively. Echocardiography showed a significant reduction in left ventricular ejection fraction (LVEF) (68.50%±4.11% vs 63.87%±4.00%, P<0.01). In post-surgery patients with CLBBB (67.46%±2.96% vs 64.83%±4.20%, P=0.082), there was a significant reduction in LVEF (69.39%±5.29% vs 63.40%±4.15%, P<0.01), while there was no statistical difference in patients without CLBBB.Conclusions Left ventricular outflow tract dredging surgery could effectively reduce the proportion of LVH in patients with hypertrophic obstructive cardiomyopathy and alleviate outflow tract obstruction. However, patients who developed CLBBB after surgery showed a tendency of reduced LVEF.