目的：探讨实习护士人文关怀品质在自我效能与临床沟通能力间的中介效应，为护理教育提供实证依据，提升护士临床沟通能力。方法：采用便利抽样法，选取2023年9月至2024年2月上海市6所三级甲等医院实习护士211名为研究对象。采用一般人口学资料调查表、一般自我效能感量表、护生临床沟通能力量表和护士人文关怀品质量表进行调查，共回收有效问卷211份（有效率100.00%）。结果：实习护士自我效能总分为（28.85±3.88）分，临床沟通能力总分为（86.01±7.36）分，人文关怀品质总分为（116.74±11.16）分。自我效能对临床沟通能力具有显著预测作用（t=10.673，P<0.01），纳入人文关怀品质后，该预测作用仍显著（t=4.685，P<0.01）。间接效应值为1.129，直接效应占总效应的55.98%，间接效应占44.02%。结论：人文关怀品质在实习护士自我效能与临床沟通能力间起中介作用。护理教育者应采取多样化策略帮助护士更好地理解患者感受，提升其人文关怀品质，从而增强临床沟通能力。

Objective The purpose of this study was to explore the mediating effect of intern nurses’ humanistic care quality on self-efficacy and clinical communication ability. Methods Convenience sampling method was used to select 211 intern nurses from six tertiary hospitals in Shanghai from September 2023 to February 2024 as research subjects. A survey was conducted using a general demographic data questionnaire, a general self-efficacy scale, a nursing student clinical communication ability scale, and a nursing humanistic care quality scale. A total of 211 valid questionnaires (100.00%) were collected. Results The study showed that the self-efficacy score of intern nurses was (28.85 ± 3.88) points, the total score of clinical communication ability was (86.01 ± 7.36) points, and the total score of humanistic care quality was (116.74 ± 11.16) points. The predictive effect of self-efficacy on clinical communication ability was significant (t=10.673, P<0.01), and after incorporating humanistic care qualities, the predictive effect of self-efficacy on clinical communication ability was still significant (t=4.685, P<0.01). The indirect effect value was 1.129, the direct effect accounts for 55.98% of total effect, and indirect effect accounts for 44.02%. Conclusions In this study, the quality of humanistic care played a partial mediating role between self-efficacy and clinical communication ability in intern nurses. Therefore, nursing educators should adopt multiple strategies to enable intern nurses to better understand the feelings of patients, improve the quality of humanistic care, to enhance their clinical communication ability.