Evaluate therapeutic efficacy of resistance training and aerobic training for gerontal patients with chronic obstructive pulmonary disease

doi:10.16138/j.1673-6087.2022.01.015

Abstract

Abstract:

Objective To evaluate the effects of resistance and aerobic training on the patients with chronic obstructive pulmonary disease (COPD). Methods A total of 80 gerontal patients with stable COPD were enrolled in this study. They were randomly assigned to a combination training group (resistance and aerobic training) or an aerobic training group, respectively, and received training for 12 weeks. Thirty-seven patients completed combined training and 35 patients completed aerobic training. The clinical information including lung function, arterial blood gas, exercise ability, St. George’s respiratary questionnaire (SGRQ) score, anxiety and depression status were evaluated, and compared among three time points(pre, post 12-week training, and 3-month follow-up). Results After 12-week training, the body mass index (BMI), partial pressure of oxygen(PaO₂), 3-minute walking distance(3MWD) and SGRQ scores in the combined training group were significantly improved compared with those before treatment(P<0.05). There were also significant differences in 3MWD and SGRQ scores after 3-month follow-up compared with their own baseline (P<0.05). The PaO₂ and 3MWD (after treatment and 3-month follow up) was significantly improved compared with those before treatment in aerobic training group(P<0.05). After 12-week training and 3-month follow-up, BMI, 3MWD and SGRQ scores in the combined training group were significantly improved compared with the aerobic training group (P<0.05), the depression state in the combined training group was also improved; while the anxiety state in the combined training group was worse than that in the aerobic training group after 3 months(P<0.05). There was no significant difference in pulmonary function, arterial blood gas analysis, heart rate and COPD assessment test between two groups(P>0.05).Conclusions The therapeutic efficacy of 12-week training of resistance and aerobic for the gerontal patients with stable COPD significantly improved their exercise ability, quality of life and BMI; and the effect on excise ability could last more than three months. However, it couldn’t make a significant change in pulmonary function.

Key words: Chronic obstructive pulmonary disease, Aerobic training, Resistance training

CLC Number:

QIU Liwen, XU Yiming, ZHANG Yin, SHEN Honghua, CHEN Shen. Evaluate therapeutic efficacy of resistance training and aerobic training for gerontal patients with chronic obstructive pulmonary disease[J]. Journal of Internal Medicine Concepts & Practice, 2022, 17(01): 78-83.

Figures/Tables 2

References 31

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参数	有氧训练组（n=35）	联合训练组（n=37）	P
年龄（岁）	75.6±7.9	76.6±5.7	0.344
男性	20（57.1）	22（59.5）	0.842
BMI（kg/m²）	21.78±2.37	22.10±2.26	0.549
吸烟[n(%)]	10（28.6）	15（40.5)	0.286
吸烟量（年支）	407±65	401±57	0.821
高血压[n（%）]	23（65.7）	22（59.5）	0.584
2型糖尿病[n（%）]	6（17.1）	8（21.6）	0.631
冠心病[n（%）]	8（22.9）	10（27.0）	0.683
FVC（L）	3.70±0.44	3.77±0.45	0.573
FEV₁（L）	2.40±0.38	2.50±0.42	0.284
FEV₁/FVC（%）	0.64±0.05	0.66±0.05	0.214
PaO₂（mmHg）	62.69±8.48	61.22±8.93	0.459
PaCO₂（mmHg）	46.94±4.96	47.81±7.59	0.570
心率（次/min）	78.97±10.37	79.51±12.87	0.845
CAT（分）	9.86±2.50	9.70±3.78	0.840
SGRQ（分）	15.46±7.75	16.65±7.77	0.520
3MWD（m）	116.66±44.78	117.62±41.97	0.925
HAMA（分）	4.00±3.27	5.05±3.24	0.174
HRSD（分）	9.11±3.72	8.03±3.48	0.205

参数	有氧训练组（n=35）	联合训练组（n=37）	P
BMI（kg/m²）
基线	21.78±2.37	22.10±2.26	0.549
治疗12周末	22.05±2.24	23.15±1.83^1）	0.025
随访3月末	21.51±2.30	22.80±2.17	0.017
FVC（L）
基线	3.70±0.44	3.77±0.45	0.573
治疗12周末	3.71±0.44	3.77±0.44	0.561
随访3月末	3.76±0.34	3.84±0.41	0.395
FEV₁（L）
基线	2.40±0.38	2.50±0.42	0.284
治疗12周末	2.41±0.37	2.53±0.43	0.202
随访3月末	2.51±0.37	2.60±0.40	0.331
FEV₁/FVC（%）
基线	0.64±0.05	0.66±0.05	0.214
治疗12周末	0.65±0.05	0.67±0.05	0.106
随访3月末	0.66±0.06	0.67±0.05	0.525
PaO₂（mmHg）
基线	62.69±8.48	61.22±8.93	0.459
治疗12周末	68.67±7.84^1）	70.89±7.88^1）	0.238
PaCO₂（mmHg）
基线	46.94±4.96	47.81±7.59	0.570
治疗12周末	45.31±4.46	47.62±5.65	0.059
心率（次/min）
基线	78.9±10.4	79.5±12.9	0.845
治疗12周末	79.3±10.8	80.0±13.3	0.803
随访3月末	78.6±9.3	83.7±13.8	0.068
CAT（分）
基线	9.86±2.50	9.70±3.78	0.840
治疗12周末	9.51±2.69	9.70±2.56	0.762
随访3月末	9.74±2.00	10.35±2.06	0.208
SGRQ（分）
基线	15.46±7.75	16.65±7.77	0.520
治疗12周末	14.94±6.45	11.75±4.23^1）	0.015
随访3月末	15.35±5.88	13.02±3.41^1）	0.042
3MWD（m）
基线	116.66±44.78	117.62±41.97	0.925
治疗12周末	139.48±44.31^1）	161.97±40.72^1）	0.028
随访3月末	133.00±51.04	155.43±42.32^1）	0.046
HAMA（分）
基线	4.00±3.27	5.05±3.24	0.174
治疗12周末	3.94±3.01	5.16±3.06	0.093
随访3月末	4.06±2.10	5.43±3.07	0.038
HRSD（分）
基线	9.11±3.72	8.03±3.48	0.205
治疗12周末	8.86±3.09	7.30±3.25	0.041
随访3月末	8.29±2.47	7.70±3.47	0.417