Original article

The result analysis and clinical significance of single urine test and renal function examination in 1 200 adults of the Bai ethnic group

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  • 1. Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    2. Center of Medical Examination, The People’s Hospital of Jianchuan, Yunnan Province, Jianchuan 671300, China

Received date: 2020-04-03

  Online published: 2022-07-26

Abstract

Objective To identify the abnormal urine test and renal function of Bai ethnic adults in Yunnan Province by analyzing their physical examination results and provide epidemiological evidence for the prevention and treatment of chronic kidney disease(CKD) in South Western China. Methods The results of single urine test and renal function of the participants receiving medical examination from January to December 2019 in the Center of Medical Examination of the People’s Hospital of Jianchuan were collected retrospectively. The CKD Epidemiology Collaboration (CKD-EPI) formula was used to calculate glomerular filtration rate(GFR) and the results were compared and analyzed between different gender and age groups. Results A total of 1 200 Bai ethnic participants were enrolled in our study and the average age was (41.64±11.55) years. 716(59.7%) cases were male and 366 cases in male (30.5%) were abnormal in the urine test, including 300 (25.0%) cases of microscopic hematuria and 113(9.4%) cases of proteinuria. The female participants had a higher prevalence of microscopic hematuria(35.9% vs 17.6%, χ2=51.88, P<0.001) than male, while the male participants had a higher prevalence of proteinuria(11.7% vs 6.0%, χ2=11.15, P<0.001). In renal function, the GFR in 87.3% of the participants was superior to 90 mL/(min·1.73㎡), only 6(0.5%) participates’ GFR were inferior to 60 mL/(min·1.73㎡). GFR decreased gradually with age. Conclusions Physical examination is an important way to screen renal diseases. The rate of abnormal urine test and renal function was high in Bai ethnic adults in Yunnan Province and it should attract the attention of clinicians.

Cite this article

GAO Chenni, DUAN Yuhua, JIA Liangqin, CHEN Xiaonong . The result analysis and clinical significance of single urine test and renal function examination in 1 200 adults of the Bai ethnic group[J]. Journal of Internal Medicine Concepts & Practice, 2021 , 16(01) : 18 -21 . DOI: 10.16138/j.1673-6087.2021.01.005

References

[1] Zhang L, Wang F, Wang L, et al. Prevalence of chronic kidney disease in China: a cross-sectional survey[J]. Lancet, 2012, 379(9818): 815-822.
[2] 王善志, 朱永俊, 唐文庄, 等. 中国成人及老年人群慢性肾脏病患病率Meta分析[J]. 中国老年学杂志, 2017, 37(21): 5384-5388.
[3] Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate[J]. Ann Intern Med, 2009, 150(9): 604-612.
[4] Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline[J]. Kidney Int Suppl, 2013, 3(1):1-150.
[5] Foreman KJ, Marquez N, Dolgert A, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories[J]. Lancet, 2018, 392(10159): 2052-2090.
[6] Li PK, Chow KM, Matsuo S, et al. Asian chronic kidney disease best practice recommendations: positional statements for early detection of chronic kidney disease from Asian Forum for Chronic Kidney Disease Initiatives (AFCKDI)[J]. Nephrology (Carlton), 2011, 16(7): 633-641.
[7] 薛宁, 丁小强, 钟一红, 等. 20 665例普通人群单次尿液和肾功能检查结果及其意义探讨[J]. 肾脏病与透析肾移植杂志, 2010, 19(2): 116-120.
[8] 谢凤燕, 解加泳, 王立珍, 等. 16 858例成年体检人群单次尿液和肾功能检查结果及临床意义[J]. 医学研究生学报, 2013, 26(2): 160-163.
[9] Wu HY, Huang JW, Peng YS, et al. Microalbuminuria screening for detecting chronic kidney disease in the general population: a systematic review[J]. Ren Fail, 2013, 35(5): 607-614.
[10] Chen W, Chen W, Wang H, et al. Prevalence and risk factors associated with chronic kidney disease in an adult population from southern China[J]. Nephrol Dial Transplant, 2009, 24(4): 1205-1212.
[11] 王彦平. 天津市宝坻区健康体检者血尿流行现况分析[J]. 国际医药卫生导报, 2018, 24(18): 2796-2798.
[12] 王晋文, 芮章茹, 任晓燕. 云南慢性肾衰竭患者病因与转归分析[J]. 昆明医学院学报, 2010, 31(10): 102-104.
[13] Levey AS, Stevens LA. Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: more accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions[J]. Am J Kidney Dis, 2010, 55(4): 622-627.
[14] 徐果, 陈志恒, 张浩, 等. 5 708例健康体检人群中慢性肾脏疾病的调查分析[J]. 中南大学学报(医学版), 2014, 39(4): 408-415.
[15] 蒋玉秀. 桂林理工大学离退休职工体检肝功能、肾功能、血脂、血糖检测结果分析[J]. 临床检验杂志(电子版), 2020, 9(1): 136-137.
[16] Vallianou NG, Mitesh S, Gkogkou A, et al. Chronic kidney disease and cardiovascular disease: is there any relationship[J]. Curr Cardiol Rev, 2019, 15(1): 55-63.
[17] 黄燕萍, 茹倩影, 张旦欢, 等. 2012-2016 年上海市长宁区老年人群慢性肾脏病患病率调查研究[J]. 中国全科医学, 2020, 23(17): 2215-2218.
[18] Li PK, Garcia-Garcia G, Lui SF, et al. Kidney health for everyone everywhere - from prevention to detection and equitable access to care[J]. Blood Purif, 2020, 11: 1-8.
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