Journal of Internal Medicine Concepts & Practice >
Analysis of therapeutic efficacy of simplified diagnosis and treatment for outpatients with acute mild ischemic stroke in designated hospitals during the COVID-19 pandemic
Received date: 2021-09-18
Online published: 2022-11-04
Objective To summarize the clinical characteristics of outpatients with acute mild stroke and analyze the therapeutic efficacy of simplified diagnosis and treatment for the patients during the period of epidemic prevention and control. Methods Eighty-seven outpatients with acute mild stroke in Beijing Men Tou Gou District Hospital from January 27 to September 27 in 2020 were enrolled as observation group (n=87). Simplified diagnosis and treatment were performed on the observation group, and the stroke-related neurologic deficits were evaluated with 7-day National Institutes of Health Stroke Scale (NIHSS) score and 90-day modified Rankin scale (mRS) score. Seventy-five patients with acute mild ischemic stroke admitted to were enrolled as control group (n=75) during the same period. The clinical characteristics, biochemistry index, 7-day NIHSS score and 90-day mRS score were analyzed and compared between control group and observation group. Results Univariate analysis showed the time from appearing stroke symptom to receiving treatment in the observation group [3(2,4) day] was significantly longer than that in the control group[ 1(0.3,3) day](Z=-4.234, P=0.000), while the infusion time of therapeutic medicine and treatment cost in observation group were significantly lower than that in control group[6(5,7) d vs 10(7,12) d, P=0.000; (5 666.05±2 343.78) yuan vs (12 590.11±3 815.52) yuan, P=0.000 ]. The two groups had no significant differences in 0-day NIHSS score, 7-day NIHSS score and 90-day mRS score (90 d mRS≤2)[2(1,3) vs 2(1,3);1(0,1) vs 1(0,3); 87.35% vs 84.00%, P>0.05]. Conclusions The patients with acute mild stroke were not necessary to be hospitalized and could be managed with simplified diagnosis and treatment in outpatient department during the period of pandemic or non-pandemic.
Key words: COVID-19; Epidemic; Mild stroke; Outpatient; Simplified diagnosis and treatment
GAO Caihong . Analysis of therapeutic efficacy of simplified diagnosis and treatment for outpatients with acute mild ischemic stroke in designated hospitals during the COVID-19 pandemic[J]. Journal of Internal Medicine Concepts & Practice, 2022 , 17(05) : 385 -389 . DOI: 10.16138/j.1673-6087.2022.05.007
[1] | Nicola M, Alsafi Z, Sohrabi C, et al. The socio-economic implications of the coronavirus pandemic (COVID-19)[J]. Int J Surg, 2020 78: 185-193. |
[2] | 王伊龙, 赵性泉, 刘新峰, 等. 高危非致残性缺血性脑血管事件诊疗指南[J]. 中国卒中杂志, 2016, 11(6): 481-491. |
[3] | Hurst K, Lee R, Sideso E, et al. Delays in the presentation to stroke services of patients with transient ischaemic attack and minor stroke[J]. Br J Surg, 2016, 103(11): 1462-1466. |
[4] | Khatri P, Conaway MR, Johnston KC, et al. Ninety-day outcome rates of a prospective cohort of consecutive patients with mild ischemic stroke[J]. Stroke, 2012, 43(2): 560-562. |
[5] | Coull AJ, Lovett JK, Rothwell PM. Population based study of early risk of stroke after transient ischaemic attack or minor stroke[J]. BMJ, 2004, 328(7435): 326. |
[6] | 中华医学会神经病学分会中华医学会神经病学分会脑血管病学组. 中国各类主要脑血管病诊断要点2019[J]. 中华神经科杂志, 2019, 52(9): 710-715. |
[7] | Schwartz JK, Capo-Lugo CE, Akinwuntan AE, et al. Classification of mild stroke[J]. PM R, 2019, 11(9): 996-1003. |
[8] | Laurencin C, Philippeau F, Blanc-Lasserre K, et al. Thrombolysis for acute minor stroke: outcome and barriers to management[J]. Cerebrovasc Dis, 2015, 40(1-2): 3-9. |
[9] | Khatri P, Conaway MR, Johnston KC, et al. Ninety-day outcome rates of a prospective cohort of consecutive patients with mild ischemic stroke[J]. Stroke, 2012, 43(2): 560-562. |
[10] | Zhao Y, Song Y, Guo Y, et al. Endovascular thrombectomy vs. medical treatment for mild stroke patients[J]. J Stroke Cerebrovasc Dis, 2020, 29(12): 105258. |
[11] | Edwards DF, Hahn M, Baum C, et al. The impact of mild stroke on meaningful activity and life satisfaction[J]. J Stroke Cerebrovasc Dis, 2006, 15(4): 151-157. |
[12] | Strambo D, Zambon AA, Roveri L, et al. Defining minor symptoms in acute ischemic stroke[J]. Cerebrovasc Dis, 2015, 39(3-4): 209-215. |
[13] | Koge J. Reperfusion therapy in patients with minor or mild ischemic stroke[J]. Rinsho Shinkeigaku, 2019, 59(2): 84-92. |
[14] | Markus HS, Brainin M. COVID-19 and stroke-A global World Stroke Organization perspective[J]. Int J Stroke, 2020, 15(4): 361-364. |
[15] | Akhtar N, Kamran S, Elkhider H, et al. Progression of stroke deficits in patients presenting with mild symptoms[J]. PloS One, 2020, 15(4): e0231448. |
[16] | Ghanchi H, Takayanagi A, Savla P, et al. Effects of the COVID-19 pandemic on stroke patients[J]. Cureus, 2020, 12(8): e9995. |
[17] | 周丽琼, 王瑞香, 褚晓凡, 等. 新型冠状病毒肺炎疫情对急性缺血性卒中患者就诊时间的影响[J]. 中风与神经疾病杂志, 2020, 37(5): 406-408. |
[18] | Luo W, Li J, Li Z, et al. Effects of the COVID-19 pandemic on reperfusion therapy for acute ischemic stroke patients in Huizhou City, China[J]. Neurol Sci, 2021, 42(2): 467-473. |
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