Journal of Internal Medicine Concepts & Practice >

2024 , Vol. 19 >Issue 06: 409 - 412

DOI: https://doi.org/10.16138/j.1673-6087.2024.06.10

Case report

A case of systemic lupus erythematosus complicated with calcinosis cutis

  • LIU Yanming ,
  • SUN Shuyu ,
  • LI Song ,
  • WU Jian
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  • Department of Rheumatology and Immunology， The First Affiliated Hospital of Soochow University， Suzhou 215000， China

Received date: 2024-09-23

  Online published: 2025-03-11

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Abstract

Calcinosis cutis is one of the complications of dermatomyositis and systemic sclerosis, while it is rare in other autoimmune diseases, especially in systemic lupus erythematosus(SLE). This article reports a female patient who had been diagnosed with SLE for 8 years ago, and developed extensive calcification, mainly affecting the limbs. Her condition improved after receiving treatment with tofacitinib. SLE patients complicated with calcinosis are rare, and their pathogenesis and treatment strategies still require doing more exploration and research. Early detection, early diagnosis, and early treatment are essential for the patients.

Key words： Systemic lupus erythematosus; Calcinosis; Complications; Rheumatic and immunologic diseases

Cite this article

LIU Yanming , SUN Shuyu , LI Song , WU Jian . A case of systemic lupus erythematosus complicated with calcinosis cutis[J]. Journal of Internal Medicine Concepts & Practice, 2024 , 19(06) : 409 -412 . DOI: 10.16138/j.1673-6087.2024.06.10

References

[1] Boulman N, Slobodin G, Rozenbaum M, et al. Calcinosis in rheumatic diseases[J]. Semin Arthritis Rheum, 2005, 34(6): 805-812.
[2] Gutierrez A Jr, Wetter DA. Calcinosis cutis in autoimmune connective tissue diseases[J]. Dermatol Ther, 2012, 25(2): 195-206.
[3] Aringer M, Costenbader K, Daikh D, et al. 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus[J]. Arthritis Rheumatol, 2019, 71(9): 1400-1412.
[4] Dawood NB, Yan KL, Shieh A, et al. Normocalcaemic primary hyperparathyroidism: an update on diagnostic and management challenges[J]. Clin Endocrinol (Oxf), 2020, 93(5): 519-527.
[5] Bhatia S, Silverberg NB, Don PC, et al. Extensive calcinosis cutis in association with systemic lupus erythematosus[J]. Acta Derm Venereol, 2001, 81(6): 446-447.
[6] Tristano AG, Villarroel JL, Rodríguez MA, et al. Calcinosis cutis universalis in a patient with systemic lupus erythematosus[J]. Clin Rheumatol, 2006, 25(1): 70-74.
[7] Khudadah M, Jawad A, Pyne D. Calcinosis cutis universalis in a patient with systemic lupus erythematosus[J]. Lupus, 2020, 29(12): 1630-1632.
[8] Powell RJ. Systemic lupus erythematosus with widespread subcutaneous fat calcification[J]. Proc R Soc Med, 1974, 67(3): 215-217.
[9] Rothe MJ, Grant-Kels JM, Rothfield NF. Extensive calcinosis cutis with systemic lupus erythematosus[J]. Arch Dermatol, 1990, 126(8): 1060-1063.
[10] Kim MS, Choi KC, Kim HS, et al. Calcinosis cutis in systemic lupus erythematosus: a case report and review of the published work[J]. J Dermatol, 2010, 37(9): 815-818.
[11] Yamamoto T, Furuhata Y, Tsuboi R. Lipomembranous changes and calcification associated with systemic lupus erythematosus[J]. Clin Exp Dermatol, 2007, 32(3): 278-280.
[12] Chevreul K, Brigham KB, Gandré C, et al. The economic burden and health-related quality of life associated with systemic sclerosis in France[J]. Scand J Rheumatol, 2015, 44(3): 238-246.
[13] Metzger AL, Singer FR, Bluestone R, et al. Failure of disodium etidronate in calcinosis due to dermatomyositis and scleroderma[J]. N Engl J Med, 1974, 291(24):1294-1296.
[14] Sousa FC, Figueiras M, Parente AR, et al. Dystrophic calcinosis cutis associated with systemic lupus erythematosus[J]. Pan Afr Med J, 2021, 40: 258.
[15] Elahmar H, Feldman BM, Johnson SR. Management of calcinosis cutis in rheumatic diseases[J]. J Rheumatol, 2022, 49(9):980-989.
[16] Balin SJ, Wetter DA, Andersen LK, et al. Calcinosis cutis occurring in association with autoimmune connective tissue disease: the Mayo Clinic experience with 78 patients, 1996-2009[J]. Arch Dermatol, 2012, 148(4):455-462.
[17] Wendel S, Venhoff N, Frye BC, et al. Successful treatment of extensive calcifications and acute pulmonary involvement in dermatomyositis with the Janus-kinase inhibitor tofacitinib[J]. J Autoimmun, 2019, 100: 131-136.
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