Review

Explore mechanism and progress of kidney-tonifying method on middle-aged and elderly essential hypertension based on traditional Chinese medicine theory of “tonifying kidney and resisting aging”

  • XU Tingyan ,
  • ZHANG Jin ,
  • GU Yun
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  • 1. Department of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medcine,Shanghai 200025,China
    2. Department of Geriatrics, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032,China

Received date: 2024-05-17

  Online published: 2025-04-30

Abstract

Hypertension is a common disease and the most important risk factor for cardiovascular diseases (CVD). Lowering blood pressure effectively and stably is the key to reduce CVD. Unlike single-mechanism drugs, traditional Chinese medicine (TCM) has the synergistic effect of multi-target and multi-mechanism on the treatment of essential hypertension. According to the theory of TCM, kidney essence deficiency and liver-yang hyperactivity are the characteristics and pathogenesis of hypertension. The method of tonifying kidney has a long history in treating hypertension, and it embodies the basic concept ‘treat disease, cure must seek the root cause’ in TCM. The article reviews the clinical studies on various kidney-tonifying methods, explores the mechanisms and summarizes the research progress, to provide reference for the clinical treatment of hypertension with the combination of traditional Chinese and Western medicine.

Cite this article

XU Tingyan , ZHANG Jin , GU Yun . Explore mechanism and progress of kidney-tonifying method on middle-aged and elderly essential hypertension based on traditional Chinese medicine theory of “tonifying kidney and resisting aging”[J]. Journal of Internal Medicine Concepts & Practice, 2025 , 20(01) : 67 -70 . DOI: 10.16138/j.1673-6087.2025.01.14

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