Journal of Internal Medicine Concepts & Practice >
Age-period-cohort analysis and prediction of burden of asthma attributed to tobacco in China from 1990 to 2019
Received date: 2024-04-24
Online published: 2025-09-01
Objective To study the burden of asthma attributed to tobacco in China from 1990 to 2019, and to provide scientific basis for asthma prevention and control. Methods Using the Global Burden of Disease (GBD) 2019 database, we analyzed the trends of standardized mortality rates and standardized disability-adjusted life year(DALY) rates of asthma attributed to tobacco in China from 1990 to 2019. An age-period-cohort model was utilized to analyze the age, period, and birth cohort effects of the mortality rate of tobacco - related asthma, and an autoregressive integrated moving average model(ARIMA) was adopted to forecast the standardized mortality rates and standardized DALY rates of tobacco-related asthma for the next 5 years (2020-2024). Results Compared to 1990, the total number of deaths attributed to tobacco-related asthma in China was 5 037 in 2019, decreased 30.40% (7 237). The total DALY in 2019 were 200 700 person - years, decreased 13.54% compared to 231 000 person - years in 1990. From 1990 to 2019, the standardized mortality rate of the total population showed a decreasing trend, with an average annual decrease rate of 4.40% (95% CI: -4.63% - -4.16%), and the standardized DALY rate of the total population also showed a downward trend, with an average annual decrease of 3.43% (95% CI: -3.80% - -3.06%). The results of age effect indicated that the mortality rate of tobacco-related asthma increased with age (35-85 years) for males and the total population, reached peak in 85-89 age group, while female’s peak was in the 95 and over age group. From the perspective of period and cohort effects, the risk of death of tobacco-related asthma decreased over time in females, males, and the total population. The forecast results showed that the standardized mortality rate would decrease from 0.17/100 000 in 2020 to 0.05/100 000 in 2024, and the standardized DALY rate would decrease from 6.61/100 000 in 2020 to 3.65/100 000 in 2024. Conclusions The burden of asthma attributed to tobacco in China has shown a downward trend in the past few decades, which is closely related to health education, medical technology progress and the implementation of public health policies. In the future, it is necessary to adjust prevention and control strategies according to the actual situation to further reduce the disease burden of asthma.
KANG Min , SHI Jing . Age-period-cohort analysis and prediction of burden of asthma attributed to tobacco in China from 1990 to 2019[J]. Journal of Internal Medicine Concepts & Practice, 2025 , 20(03) : 242 -247 . DOI: 10.16138/j.1673-6087.2023.03.09
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