外科理论与实践 ›› 2025, Vol. 30 ›› Issue (2): 106-111.doi: 10.16139/j.1007-9610.2025.02.03

• 专家论坛 • 上一篇    下一篇

延迟诊断的胆囊癌手术治疗的争议焦点

乐森1, 左越1, 邓正栋2(), 王剑明2()   

  1. 1.武汉科技大学附属天佑医院,湖北 武汉 430064
    2.华中科技大学同济医学院附属同济医院,湖北 武汉 430030
  • 收稿日期:2025-01-29 出版日期:2025-03-25 发布日期:2025-07-07
  • 通讯作者: 王剑明,E-mail: wjm18jgm@aliyun.com
    邓正栋,E-mail: dengzhengdong0915@163.com
  • 基金资助:
    国家自然科学基金(82373032)

Controversial points in the surgical treatment of gallbladder cancer with delayed diagnoses

LE Sen1, ZUO Yue1, DENG Zhengdong2(), WANG Jianming2()   

  1. 1. Tianyou Hospital,Wuhan University of Science and Technology,Hubei Wuhan 430064,China
    2. Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Wuhan 430030, China
  • Received:2025-01-29 Online:2025-03-25 Published:2025-07-07

摘要:

延迟诊断的胆囊癌作为胆囊良性疾病术中或术后意外确诊的恶性肿瘤,根治性手术治疗是其核心的治疗方法,目前再次手术必要性、手术时机选择、术式选择、切除范围界定、术前新辅助治疗仍存在一定争议。延迟诊断的胆囊癌再次手术需平衡肿瘤根治、术后风险及生存获益,并结合新辅助治疗对根治性治疗的促进作用,制定个体化方案。多学科团队应整合创新技术与多中心前瞻性研究,推动延迟诊断的胆囊癌治疗策略的精准化发展,优化病人生存结局。

关键词: 延迟诊断的胆囊癌, 根治性手术, 腹腔镜手术, 新辅助治疗

Abstract:

Gallbladder cancer with delayed diagnoses, as a malignant tumor diagnosed intraoperatively or postoperatively incidentally in benign gallbladder diseases, radical surgical treatment is its core treatment, and the necessity of re-operation, timing of surgery, choice of surgical procedure, definition of resection extent, and preoperative neoadjuvant therapy still remain controversial. Re-operation for gallbladder cancer with delayed diagnoses needs to balance tumor radicalization, postoperative risk, and survival benefit, and combining neoadjuvant therapy to facilitate radical treatment, and develop individualized protocols. The multidisciplinary team should integrate innovative technologies and multi-center prospective studies to promote the development of precise treatment strategies for gallbladder cancer with delayed diagnoses and optimize the survival of patients.

Key words: Gallbladder cancer with delayed diagnoses, Radical surgery, Laparoscopic surgery, Neoadjuvant therapy

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