外科理论与实践

外科理论与实践 >

2021 , Vol. 26 >Issue 06: 556 - 560

DOI: https://doi.org/10.16139/j.1007-9610.2021.06.019

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口服利福平联合超声引导穿刺治疗肉芽肿小叶性乳腺炎的回顾性研究

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  • 宁波大学附属人民医院甲乳外科，浙江 宁波 315040

收稿日期: 2020-03-11

  网络出版日期: 2022-07-27

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Retrospective study on oral administration of rifampicin combined with ultrasound-guided puncture in treatment of granulomatous lobular mastitis

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  • Department of Thyroid and Breast, the Affiliated People’s Hospital of Ningbo University, Zhejiang Ningbo 315040, China

Received date: 2020-03-11

  Online published: 2022-07-27

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摘要

目的：研究口服利福平联合超声穿刺治疗肉芽肿小叶性乳腺炎（granulomatous lobular mastitis, GLM）的疗效。方法：收集2017年1月至2019年1月我院收治经粗针穿刺病理诊断为GLM的10例病人临床资料，中位年龄为34岁。分析口服利福平（剂量为每天2次，每次300 mg，疗程为9个月）联合超声穿刺抽脓治疗3、6、9、12个月后的临床症状和超声检查结果。结果：所有病人均有母乳喂养史。有急性期乳房表现和局部病变，5例伴乳房脓肿。治疗12个月后，随访所有病人临床症状均消失，且超声检查结果正常。随访12个月内未见复发。结论：口服利福平联合超声穿刺治疗GLM病人效果显著。

关键词： 肉芽肿小叶性乳腺炎; 利福平; 超声引导穿刺

本文引用格式

仇伊尔, 邬颖杰, 仇骞慧, 陆国文 . 口服利福平联合超声引导穿刺治疗肉芽肿小叶性乳腺炎的回顾性研究[J]. 外科理论与实践, 2021 , 26(06) : 556 -560 . DOI: 10.16139/j.1007-9610.2021.06.019

Abstract

Objective To study the efficacy of oral administration of rifampicin combined with ultrasound-guided puncture for granulomatous lobular mastitis (GLM). Methods From January 2017 and January 2019，10 GLM patients with median age of 34 years confirmed by pathology were included in this study and treated with oral administration of rifampicin, 300 mg twice daily for a period of 9 months, combined with ultrasound-guided puncture. The symptoms and ultrasound manifestations of GLM patients were investigated at 3, 6, 9, 12 months, respectively. Results All patients had a history of breast feeding and manifestation of acute stages of breast infection, 5 cases with breast abscess. After 12 months therapy, the symptoms disappeared in all patients with normal ultrasonic manifestation and no patient relapsed. Conclusions Oral administration of rifampicin combined with ultrasound-guided puncture could be effective in the treatment of GLM patients.

Key words： Granulomatous lobular mastitis; Rifampicin; Ultrasound-guided puncture

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