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下肢静脉曲张合并非血栓性髂静脉压迫的诊疗策略

  • 丁财有 ,
  • 吴劲进 ,
  • 朱越锋
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  • 1.浙江大学医学院附属第四医院,国际医学院,国际健康医学研究院,普外科,浙江 义乌 322000
    2.浙江大学医学院附属邵逸夫医院血管外科,浙江 杭州 310020
朱越锋,E-mail: srrshzyf@zju.edu.cn

收稿日期: 2024-10-21

  网络出版日期: 2025-03-17

基金资助

浙江省中医药科学研究基金资助项目(2011ZB079);浙江省医药卫生科技项目(2024KY1184)

Diagnostic and treatment strategies for varicose veins of lower extremities combined with non-thrombotic iliac vein lesion

  • DING Caiyou ,
  • WU Jingjin ,
  • ZHU Yuefeng
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  • 1. Department of General Surgery, the Fourth Affiliated Hospital of School of Medicine, International School of Medicine, International Institutes of Medicine, Zhejiang University, Zhejiang Yiwu, 322000 China
    2. Department of Vascular Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Zhejiang Hangzhou 310020, China

Received date: 2024-10-21

  Online published: 2025-03-17

摘要

下肢静脉曲张合并非血栓性髂静脉压迫在临床上并不少见,两者的临床表现相似,但其严重程度并无线性相关性,因此需要详尽的检查后个体化分析病人的病因,进而拟定治疗策略。同期处理两种疾病可以同时解决深、浅静脉问题,加快改善临床症状,尤其是静脉性溃疡愈合,但其整体费用高,且存在医保超支等问题,而分期处理两种疾病可以密切随访后决定是否进行另一疾病治疗,但存在疾病进展风险。本文就下肢静脉曲张和非血栓性髂静脉压迫两种疾病的病因、诊断、分级、治疗等进行文献综述,探讨最佳的治疗策略。

本文引用格式

丁财有 , 吴劲进 , 朱越锋 . 下肢静脉曲张合并非血栓性髂静脉压迫的诊疗策略[J]. 外科理论与实践, 2024 , 29(06) : 487 -492 . DOI: 10.16139/j.1007-9610.2024.06.05

Abstract

The co - existence of lower extremity varicose veins and non - thrombotic iliac vein lesions is not uncommon in clinical practice. The clinical manifestations of the two are similar, but there is no linear correlation between their severity. Therefore, a thorough examination is required to individually analyze the causes of patients, and then formulate treatment strategies. Treating the two diseases simultaneously can resolve both superficial and deep venous issues, accelerate the improvement of clinical symptoms, especially the healing of venous ulcers. However, the overall cost is high, and there are issues such as exceeding medical insurance limits. Treating the two diseases in stages allows for a decision on whether to treat the other disease after close follow - up, but there is a risk of disease progression. This article reviewed the literature on the etiology, diagnosis, grading, and treatment of lower extremity varicose veins and non - thrombotic iliac vein lesions, and explored the optimal treatment strategies.

参考文献

[1] DE MAESENEER M G, KAKKOS S K, AHERNE T, et al. Editor's choice - European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines on the management of chronic venous disease of the lower limbs[J]. Eur J Vasc Endovasc Surg, 2022, 63(2):184-267.
[2] ASLAM M R, MUHAMMAD ASIF H, AHMAD K, et al. Global impact and contributing factors in varicose vein disease development[J]. SAGE Open Med, 2022,10:20503121221118992.
[3] 苏苗苗, 吴继东. 腔内射频消融术治疗大隐静脉曲张患者的临床疗效[J]. 血管与腔内血管外科杂志, 2020, 6(4):362-366.
  SU M M, WU J D. Clinical effect of endovenous radiofrequency ablation in the treatment of varicose great saphenous vein[J]. J Vasc Endovasc Surg, 2020, 6(4):362-366.
[4] LI H L, KWAN K J S, CHAN Y C, et al. Prevalence and predictors of radiological left common iliac vein compression in asymptomatic patients[J]. J Vasc Surg Venous Lymphat Disord, 2024, 12(1):101661.
[5] YE K, LU X, LI W, et al. Long-term outcomes of stent placement for symptomatic nonthrombotic iliac vein compression lesions in chronic venous disease[J]. J Vasc Interv Radiol, 2012, 23(4):497-502.
[6] 史孟杰. 下肢静脉曲张合并非血栓性髂静脉压迫综合征诊疗研究[D]. 山东: 山东大学, 2020.
  SHI M J. Diagnosis and treatment of varicose veins of lower extremities combined with non - thrombotic iliac vein compression syndrome[D]. Shandong: Shandong Univ, 2020.
[7] ZENG M, TENG B, ZHAO Y, et al. Effectiveness of iliac vein stenting combined with endovenous laser treatment of recurrent varicose veins associated with iliac vein compression[J]. Quant Imaging Med Surg, 2023, 13(9):5986-5995.
[8] HAN Y, TIAN Y, GAO L, et al. Clinical outcomes of different endovenous procedures among patients with varicose veins and iliac vein compression: a retrospective cohort study[J]. Int J Surg, 2022,101:106641.
[9] POYYAMOLI S, MEHTA P, CHERIAN M, et al. May-Thurner syndrome[J]. Cardiovasc Diagn Ther, 2021, 11(5):1104-1111.
[10] MAY R, THURNER J. The cause of the predominantly sinistral occurrence of thrombosis of the pelvic veins[J]. Angiology, 1957, 8(5):419-427.
[11] COCKETT F B, THOMAS M L. The iliac compression syndrome[J]. Br J Surg, 1965, 52(10):816-821.
[12] KIBBE M R, UJIKI M, GOODWIN A L, et al. Iliac vein compression in an asymptomatic patient population[J]. J Vasc Surg, 2004, 39(5):937-943.
[13] YOUNG V A, OBI C, OLADINI L K, et al. Venous compressive disorders[J]. Tech Vasc Interv Radiol, 2024, 27(2):100964.
[14] CHEN Z H, HUANG Y, WANG L P, et al. Preliminary study of hemodynamics of iliac venous compression syndrome using magnetic resonance imaging[J]. J Vasc Surg Venous Lymphat Disord, 2022, 10(1):131-138.e3.
[15] LI J, CHEN H, CHEN W, et al. Novel typing of iliac vein compression in asymptomatic individuals evaluated by contrast enhanced CT[J]. Surg Radiol Anat, 2021, 43(7):1149-1157.
[16] JAYARAJ A, ROSSI F H, LURIE F, et al. Diagnosis of chronic iliac venous obstruction[J]. J Vasc Surg Venous Lymphat Disord, 2024, 12(4):101744.
[17] LAU I, PNG C Y M, ESWARAPPA M, et al. Defining the utility of anteroposterior venography in the diagnosis of venous iliofemoral obstruction[J]. J Vasc Surg Venous Lymphat Disord, 2019, 7(4):514-521.e4.
[18] BRINEGAR K N, SHETH R A, KHADEMHOSSEINI A, et al. Iliac vein compression syndrome: clinical, imaging and pathologic findings[J]. World J Radiol, 2015, 7(11):375-381.
[19] MCDERMOTT S, OLIVEIRA G, ERGüL E, et al. May-Thurner syndrome: can it be diagnosed by a single MR venography study[J]. Diagn Interv Radiol, 2013, 19(1):44-48.
[20] O’SULLIVAN G J, SEMBA C P, BITTNER C A, et al. Endovascular management of iliac vein compression (May-Thurner) syndrome[J]. J Vasc Interv Radiol, 2000, 11(7):823-836.
[21] MASUDA E, OZSVATH K, VOSSLER J, et al. The 2020 appropriate use criteria for chronic lower extremity venous disease of the American Venous Forum, the Society for Vascular Surgery, the American Vein and Lymphatic Society, and the Society of Interventional Radiology[J]. J Vasc Surg Venous Lymphat Disord,2020, 8(4):505-525.e4.
[22] 中国医师协会血管外科医师分会静脉学组. 常见静脉疾病诊治规范(2022年版)[J]. 中华血管外科杂志, 2022, 7(1):12-29.
  Venous Group, Vascular Surgeons Branch, Chinese Medical Doctor Association. Diagnosis and treatment standard of common venous diseases (2022 version)[J]. Chin J Vasc Surg, 2022, 7(1):12-29.
[23] LIU P, PENG J, ZHENG L, et al. Application of computed tomography venography in the diagnosis and seve-rity assessment of iliac vein compression syndrome: a retrospective study[J]. Medicine (Baltimore), 2018, 97(34):e12002.
[24] ASSI I Z, LYNCH S R, RICKER B D, et al. A comparative study of altered hemodynamics in iliac vein compression syndrome[J]. Front Bioeng Biotechnol, 2024,12:1302063.
[25] YOUN Y J, LEE J. Chronic venous insufficiency and varicose veins of the lower extremities[J]. Korean J Intern Med, 2019, 34(2):269-283.
[26] RAFFETTO J D, MANNELLO F. Pathophysiology of chronic venous disease[J]. Int Angiol, 2014, 33(3):212-221.
[27] GOLDMAN M P, FRONEK A. Anatomy and pathophy-siology of varicose veins[J]. J Dermatol Surg Oncol, 1989, 15(2):138-145.
[28] DZIECIUCHOWICZ ?, KRZY?A?SKI R, KRUSZYNA ?, et al. Prevalence of non-thrombotic iliac vein lesions in patients with unilateral primary varicose veins[J]. Eur J Vasc Endovasc Surg, 2016, 51(3):429-433.
[29] CHENG L, ZHAO H, ZHANG F X. Iliac vein compression syndrome in an asymptomatic patient population: a prospective study[J]. Chin Med J (Engl), 2017, 130(11):1269-1275.
[30] YANG L, LIU J, CAI H, et al. The clinical outcome of a one-stop procedure for patients with iliac vein compression combined with varicose veins[J]. J Vasc Surg Venous Lymphat Disord, 2018, 6(6):696-701.
[31] HU H, HU L, DENG Z, et al. A prognostic nomogram for recurrence survival in post-surgical patients with varicose veins of the lower extremities[J]. Sci Rep, 2024, 14(1):5486.
[32] KONG J, LIU P, LI J, et al. Surgical treatment of recurrent varicose veins in the lower limbs associated with endovascular treatment of iliac vein stenosis[J]. Int J Surg, 2018,50:110-113.
[33] LI X, ZHANG H, NIU L, et al. Clinical outcomes of radiofrequency ablation for patients with varicose veins of the lower extremities combined with grade Ⅱ iliac vein compression[J]. J Vasc Surg Venous Lymphat Disord, 2021, 9(3):676-682.e2.
[34] DZIECIUCHOWICZ L, TOMCZAK J, KRUSZYNA L. The influence of non-thrombotic iliac vein stenosis on clinical course and recurrence of primary varicose veins[J]. Pol Przegl Chir, 2022, 95(4):1-5.
[35] ROSSI F H, KAMBARA A M, IZUKAWA N M, et al. Randomized double-blinded study comparing medical treatment versus iliac vein stenting in chronic venous di-sease[J]. J Vasc Surg Venous Lymphat Disord, 2018, 6(2):183-191.
[36] YANG X, WU X, PENG Z, et al. Outcomes of endovenous laser ablation with additional iliac vein stenting of nonthrombotic lesions in patients presenting with active venous ulcers[J]. J Vasc Surg Venous Lymphat Disord, 2021, 9(6):1517-1525.
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