Abstract: Objective To evaluate the safety and efficacy of laser ablation in the treatment of perforating veins from lower limb venous ulcer. Methods A total of 28 cases with chronic venous ulcer admitted between January 2014 to December 2015 were concluded in this study. Localization and mark of the perforating veins were done with CTV. High ligation was performed in all cases with great or small saphenous vein. Then half of them underwent the procedure of laser ablation to perforating venous in 14 cases as laser group. The other 14 cases were treated by ligation of perforating veins after high ligation of great or small saphenous veins as control group. Compression with local therapy of ulcer postoperatively and 2 year of follow-up were given for all the cases. Results There was no difference of general information in 2 groups. The ulcer area and history of venous ulcer were similar in both groups before operation. The decrease in ulcer area of postoperative first week in laser group was much more than that in control group (P< 0.05). However the decrease in ulcer area was similar in postoperative 1 month and 2 month between 2 groups. Six cases（42.9%） in control group and one in laser group had wound complication(P< 0.01). Complete healing of ulcer within 2 months was obtained in 12(85.7%) cases both group. The recurrence rate within 1 year was similar between 2 groups(P> 0.05) and no recurrence was present between 1 to 2 year in 2 groups. Conclusions Laser ablation of perforating vein can effectively promote the healing of ulcer after high ligation of great or small saphenous vein.

Key words: Lower limbs, Vein, Ulcer, Laser