Objective To explore the effect of early and controlling fluid resuscitation on clinical prognosIs of the patients with severe acute pancreatitis(SAP). Methods A total of 61 patients with SAP treated within 72 hours attack in Emergency Intensive Care Unit between 2012 and 2017 were included and divided into ccntrol group and uncontrol group according to whether or not reaching the goals of early and controlling fluid resuscitation. Control group included 38 patients and uncontrol group included 23 patients. Prognosis of the patients was compared between 2 groups. Results There was no obvious difference of baseline between 2 groups. The patients in control group received more fluid infusion than in uncontrol group (5 493±1 887 vs 3 967±1 203, P<0.05). The patients in control group had lower mortality than in uncontrol group (18.4% vs 47.8%, P<0.05) and lower rate of renal failure within 7 days (21.1% vs 60.9%, P<0.05), surgical intervention rate (23.6% vs 56.5%, P<0.05). There was no difference in both groups of duration of mechanical ventilation(P=0.23), pulmonary(P=1.00) and circulatory failure rate within 7 days(P=0.27). Conclusions The patients with SAP reached the goals of early and controlling fluid resuscitation might have lower mortality, lower rate of renal failure within 7 days and surgical intervention rate compared with the patients in uncontrol group,
SUN Wenwu, QI Mengzhi, MAO Enqiang
. Effect of early and controlling fluid resuscitation on prognosis of severe acute pancreatitis[J]. Journal of Surgery Concepts & Practice, 2018
, 23(01)
: 37
-40
.
DOI: 10.16139/j.1007-9610.2018.01.009
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